Medicines labeled for the same conditions
Alternatives to brexpiprazole
40 other medicines are given the same way (oral) and in the same FDA class as brexpiprazole or labeled mainly for the same use (depression); 12 are in its class, atypical antipsychotics: quetiapine, aripiprazole, olanzapine, risperidone and 8 more; the others include 8 tricyclic antidepressants, 7 serotonin reuptake inhibitors and 4 serotonin and norepinephrine reuptake inhibitors (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $0.0368 per risperidone 0.25 mg tablet (what pharmacies paid in the NADAC survey; strengths differ).
Which medicines are labeled for the same conditions as brexpiprazole?
The first 24 of the 40, the same class first. Depression lists all 37 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.
| Medicine and FDA class | Shared indication | Generic labelers (oral) | Pharmacy cost | Boxed warning | Shortage |
|---|---|---|---|---|---|
| Brexpiprazoleatypical antipsychotic | this medicine | 1 labeler | $49.50 per tablet 0.25 mg tablet | Yes | No current entry |
| Quetiapineatypical antipsychotic · same class | Depression, Schizophrenia | 50 labelers | $0.127 per tablet 300 mg tablet | Yes | No current entry |
| Aripiprazoleatypical antipsychotic · same class | Depression, Schizophrenia | 47 labelers | $0.110 per tablet 5 mg tablet | Yes | No current entry |
| Olanzapineatypical antipsychotic · same class | Depression, Schizophrenia | 33 labelers | $0.147 per tablet 20 mg tablet | Yes | No current entry |
| Risperidoneatypical antipsychotic · same class | Schizophrenia | 35 labelers | $0.0368 per tablet 0.25 mg tablet | Yes | No current entry |
| Lurasidoneatypical antipsychotic · same class | Depression, Schizophrenia | 29 labelers | $0.142 per tablet 20 mg tablet | Yes | No current entry |
| Ziprasidoneatypical antipsychotic · same class | Schizophrenia | 16 labelers | $0.269 per capsule 20 mg capsule | Yes | No current entry |
| Paliperidoneatypical antipsychotic · same class | Schizophrenia | 18 labelers | $0.972 per tablet 3 mg tablet | Yes | No current entry |
| Clozapineatypical antipsychotic · same class | Schizophrenia | 11 labelers | $0.610 per tablet 100 mg tablet | Yes | No current entry |
| Iloperidoneatypical antipsychotic · same class | Schizophrenia | 1 labeler | $60.01 per tablet 12 mg tablet | Yes | No current entry |
| Fluoxetine and olanzapineserotonin reuptake inhibitor · same class | Depression | 3 labelers | $3.44 per unit 3-25 mg | Yes | No current entry |
| Cariprazineatypical antipsychotic · same class | Depression, Schizophrenia | none listed | $50.84 per capsule 1.5 mg capsule | Yes | No current entry |
| Lumateperoneatypical antipsychotic · same class | Depression, Schizophrenia | none listed | $57.24 per capsule 10.5 mg capsule | Yes | No current entry |
| Bupropionaminoketone | Depression | 73 labelers | $0.0785 per tablet 150 mg tablet | Yes | No current entry |
| Venlafaxineserotonin and norepinephrine reuptake inhibitor | Depression | 62 labelers | $0.0799 per capsule 75 mg capsule | Yes | No current entry |
| Fluoxetineserotonin reuptake inhibitor | Depression | 59 labelers | $0.0519 per capsule 40 mg capsule | Yes | No current entry |
| Sertralineserotonin reuptake inhibitor | Depression | 48 labelers | $0.0507 per tablet 100 mg tablet | Yes | No current entry |
| Amitriptylinetricyclic antidepressant | Depression | 36 labelers | $0.03 per tablet 10 mg tablet | Yes | No current entry |
| Duloxetineserotonin and norepinephrine reuptake inhibitor | Depression | 45 labelers | $0.102 per capsule 30 mg capsule | Yes | No current entry |
| Doxepintricyclic antidepressant | Depression | 48 labelers | $0.0779 per capsule 10 mg capsule | Yes | No current entry |
| Paroxetineserotonin reuptake inhibitor | Depression | 45 labelers | $0.0611 per tablet 20 mg tablet | Yes | No current entry |
| Trazodoneserotonin reuptake inhibitor | Depression | 38 labelers | $0.0307 per tablet 50 mg tablet | Yes | No current entry |
| Escitalopramserotonin reuptake inhibitor | Depression | 44 labelers | $0.0632 per tablet 20 mg tablet | Yes | No current entry |
| Mirtazapine | Depression | 36 labelers | $0.063 per tablet 15 mg tablet | Yes | No current entry |
| Citalopramserotonin reuptake inhibitor | Depression | 35 labelers | $0.026 per tablet 10 mg tablet | Yes | No current entry |
Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)
What do pharmacies pay for each?
The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
What next?
- Brexpiprazole: the full record
- label, generics, price, shortages, recalls
- Brexpiprazole vs quetiapine
- two records side by side
- Brexpiprazole vs aripiprazole
- two records side by side
- Brexpiprazole vs olanzapine
- two records side by side
- Brexpiprazole vs risperidone
- two records side by side