Rasagiline and Dopamine Interaction
Drug interaction information between Rasagiline and Dopamine.
Rasagiline and Dopamine have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Rasagiline and Dopamine. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
These two drugs work against each other in the brain, which can stop rasagiline from doing its job.
FDA Label Information
7.8 Dopaminergic Antagonists It is possible that dopamine antagonists, such as antipsychotics or metoclopramide, could diminish the effectiveness of rasagiline.
Rasagiline Also Interacts With
- Meperidine moderate
- Dextromethorphan moderate
- Tranylcypromine moderate
- Ciprofloxacin minor
- Norepinephrine minor
Dopamine Also Interacts With
- Carbidopa/Levodopa moderate
- Deutetrabenazine moderate
- Digoxin moderate
- Tetrabenazine moderate
- Tranylcypromine moderate
Frequently Asked Questions
What SPL severity band is on file for Rasagiline + Dopamine?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Dopamine has 28 labeled pairs on file vs Rasagiline's 7. In the minor band specifically: Rasagiline has 4 (also Ciprofloxacin, Norepinephrine, Metoclopramide); Dopamine has 23 (also Amitriptyline, Doxepin, Linezolid, Nortriptyline).
What mechanism field is on file for Rasagiline and Dopamine?
These two drugs work against each other in the brain, which can stop rasagiline from doing its job.
Dopamine's labeled portfolio outnumbers Rasagiline
SPL source-record counts only. This page's band is minor · classes on file: Rasagiline (MAO-B Inhibitor); Dopamine (Inotropic / Vasopressor).
0 major · 3 moderate · 4 minor · 7 total
- Other minor peers for Rasagiline
- Ciprofloxacin
- Norepinephrine
- Metoclopramide
0 major · 5 moderate · 23 minor · 28 total
- Other minor peers for Dopamine
- Amitriptyline
- Doxepin
- Linezolid
- Nortriptyline
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.