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What the FDA labels say about taking them together

Ciprofloxacin and rasagiline

Rasagiline's FDA label of June 30, 2020 names ciprofloxacin in its drug interactions section; the ciprofloxacin labels PlainMeds reads (3) do not name rasagiline. The rasagiline label: “… and concomitant medications that increase rasagiline plasma levels (e.g., ciprofloxacin).”

Check it at the source: the ciprofloxacin FDA label on DailyMed (effective March 2, 2026, Bayer HealthCare Pharmaceuticals Inc.); the rasagiline FDA label on DailyMed (effective June 30, 2020, Teva Pharmaceuticals USA, Inc.).

What does the ciprofloxacin label say about rasagiline?

Ciprofloxacin's label (effective March 2, 2026) and its 2 other brand-application labels do not name rasagiline in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Cipro), Bayer HealthCare Pharmaceuticals Inc., effective March 2, 2026 (SPL set 888dc7f9-ad9c-4c00-8d50-8ddfd9bd27c0), via openFDA; the full label on DailyMed

What does the rasagiline label say about ciprofloxacin?

Rasagiline label, drug interactions

Rasagiline plasma concentrations may increase up to 2 fold in patients using concomitant ciprofloxacin and other CYP1A2 inhibitors.

Rasagiline label, warnings and precautions

Before initiating treatment with rasagiline, patients should be advised of the potential to develop drowsiness and specifically asked about factors that may increase the risk with rasagiline such as concomitant sedating medications, the presence of sleep disorders, and concomitant medications that increase rasagiline plasma levels (e.g., ciprofloxacin) [see Drug Interactions ( 7.6 )].

Source: FDA drug label (Rasagiline), Teva Pharmaceuticals USA, Inc., effective June 30, 2020 (SPL set e802c83c-e581-4a11-b83d-1df47120078d), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

54Ciprofloxacin generic labelers
14Rasagiline generic labelers
CiprofloxacinRasagiline
Labeled forDiarrhea, Urinary tract infections, Bacterial infectionsParkinson's disease
Boxed warningYesNo
Pharmacy cost (NADAC)$0.123 per tablet 500 mg tablet$0.521 per tablet 0.5 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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