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What the FDA labels say about taking them together

Albuterol and insulin degludec

Insulin degludec's FDA label of July 1, 2022 names albuterol in its drug interactions section; the albuterol labels PlainMeds reads (4) do not name insulin degludec. The insulin degludec label: “Drugs That May Decrease the Blood Glucose Lowering Effect of Insulin Degludec Drugs: Atypical antipsychotics, corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives …”

Check it at the source: the albuterol FDA label on DailyMed (effective April 30, 2026, Ritedose Pharmaceuticals, LLC); the insulin degludec FDA label on DailyMed (effective July 1, 2022, Novo Nordisk Pharma, Inc.).

What does the albuterol label say about insulin degludec?

Albuterol's label (effective April 30, 2026) and its 3 other brand-application labels do not name insulin degludec in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Albuterol Sulfate Inhalation Solution), Ritedose Pharmaceuticals, LLC, effective April 30, 2026 (SPL set d4c532be-1f41-60d3-e053-2995a90a98be), via openFDA; the full label on DailyMed

What does the insulin degludec label say about albuterol?

Insulin degludec label, drug interactions

Drugs That May Decrease the Blood Glucose Lowering Effect of Insulin Degludec Drugs: Atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol, epinephrine, terbutaline), and thyroid hormones. Intervention: Dosage increases and increased frequency of glucose monitoring may be required when Insulin Degludec is co-administered with these drugs.

Source: FDA drug label (Insulin Degludec), Novo Nordisk Pharma, Inc., effective July 1, 2022 (SPL set c1be283d-4b1d-4996-b2a7-4488dbff3037), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

40Albuterol generic labelers
0Insulin degludec generic labelers
AlbuterolInsulin degludec
Labeled forAsthmaType 2 diabetes, Type 1 diabetes
Boxed warningNoNo
Pharmacy cost (NADAC)$0.288 per tablet 2 mg tablet$11.39 per mL 100 unit/mL pen
Shortage nowResolvedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?