Hydralazine and Alosetron Interaction

Drug interaction information between Hydralazine and Alosetron.

Hydralazine and Alosetron have a documented minor interaction in FDA labeling.

FDA drug labeling documents a minor-severity interaction between Hydralazine and Alosetron. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.

Drug A

Hydralazine

Vasodilator

Drug B

Alosetron

5-HT3 Antagonist (IBS-D)

How They Interact

Alosetron may interfere with the way your body processes hydralazine, potentially leading to higher drug levels.

FDA Label Information

Although not studied with alosetron, inhibition of N-acetyltransferase may have clinically relevant consequences for drugs such as isoniazid, procainamide, and hydralazine.

Hydralazine Also Interacts With

View all Hydralazine interactions →

Frequently Asked Questions

What SPL severity band is on file for Hydralazine + Alosetron?

Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.

Which drug in this pair has the larger labeled-interaction portfolio?

Alosetron has 12 labeled pairs on file vs Hydralazine's 3. In the minor band specifically: Hydralazine has 3 (also Enalapril, Pindolol); Alosetron has 9 (also Estradiol, Ketoconazole, Theophylline, Cimetidine).

What mechanism field is on file for Hydralazine and Alosetron?

Alosetron may interfere with the way your body processes hydralazine, potentially leading to higher drug levels.

Alosetron's labeled portfolio outnumbers Hydralazine

SPL source-record counts only. This page's band is minor · classes on file: Hydralazine (Vasodilator); Alosetron (5-HT3 Antagonist (IBS-D)).

Hydralazine

0 major · 0 moderate · 3 minor · 3 total

Alosetron

0 major · 3 moderate · 9 minor · 12 total

Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.