Dutasteride/Tamsulosin and Furosemide Interaction
Drug interaction information between Dutasteride/Tamsulosin and Furosemide.
Dutasteride/Tamsulosin and Furosemide have a documented major interaction in FDA labeling.
FDA drug labeling documents a major-severity interaction between Dutasteride/Tamsulosin and Furosemide. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Furosemide can slightly decrease the levels of tamsulosin in your body, but it does not change how well the water pill works.
FDA Label Information
7.5 Furosemide Tamsulosin Tamsulosin had no effect on the pharmacodynamics (excretion of electrolytes) of furosemide. While furosemide produced an 11% to 12% reduction in tamsulosin hydrochloride C max and AUC, these changes are expected to be clinically insignificant and do not require adjustment of the dose of tamsulosin [see Clinical Pharmacology ( 12.3 ) ] .
Dutasteride/Tamsulosin Also Interacts With
- Tamsulosin moderate
- Warfarin moderate
- Paroxetine minor
- Atenolol minor
- Diltiazem minor
Furosemide Also Interacts With
- Dutasteride major
- Tamsulosin major
- Cyclosporine moderate
- Lithium moderate
- Oxaprozin moderate
Frequently Asked Questions
What SPL severity band is on file for Dutasteride/Tamsulosin + Furosemide?
Compiled FDA labeling labels this pair major. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Furosemide has 36 labeled pairs on file vs Dutasteride/Tamsulosin's 15. In the major band specifically: Dutasteride/Tamsulosin has 1; Furosemide has 3 (also Dutasteride, Tamsulosin).
What mechanism field is on file for Dutasteride/Tamsulosin and Furosemide?
Furosemide can slightly decrease the levels of tamsulosin in your body, but it does not change how well the water pill works.
Furosemide carries more major-labeled pairs than Dutasteride/Tamsulosin
SPL source-record counts only. This page's band is major · classes on file: Dutasteride/Tamsulosin (5-ARI / Alpha-Blocker Combination); Furosemide (Loop Diuretic).
Furosemide has 3 major-labeled pairs vs Dutasteride/Tamsulosin's 1.
1 major · 2 moderate · 12 minor · 15 total
Dutasteride/Tamsulosin has no other major-band peer in this dataset besides Furosemide.
3 major · 4 moderate · 29 minor · 36 total
- Other major peers for Furosemide
- Dutasteride
- Tamsulosin
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.