Delafloxacin and Sucralfate Interaction
Drug interaction information between Delafloxacin and Sucralfate.
Delafloxacin and Sucralfate have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Delafloxacin and Sucralfate. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Sucralfate can stick to the antibiotic in your stomach and prevent your body from absorbing it properly.
FDA Label Information
7 DRUG INTERACTIONS 7.1 Chelation Agents: Antacids, Sucralfate, Metal Cations, Multivitamins Fluoroquinolones form chelates with alkaline earth and transition metal cations. Oral administration of BAXDELA with antacids containing aluminum or magnesium, with sucralfate, with metal cations such as iron, or with multivitamins containing iron or zinc, or with formulations containing divalent and trivalent cations such as didanosine buffered tablets for oral suspension or the pediatric powder for oral solution, may substantially interfere with the absorption of BAXDELA, resulting in systemic...
Sucralfate Also Interacts With
- Theophylline major
- Naproxen moderate
- Warfarin minor
- Ketoconazole minor
- Ciprofloxacin minor
Frequently Asked Questions
What SPL severity band is on file for Delafloxacin + Sucralfate?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Sucralfate has 20 labeled pairs on file vs Delafloxacin's 2. In the minor band specifically: Delafloxacin has 2 (also Zinc Sulfate); Sucralfate has 18 (also Warfarin, Ketoconazole, Ciprofloxacin, Ofloxacin).
What mechanism field is on file for Delafloxacin and Sucralfate?
Sucralfate can stick to the antibiotic in your stomach and prevent your body from absorbing it properly.
Sucralfate carries more major-labeled pairs than Delafloxacin
SPL source-record counts only. This page's band is minor · classes on file: Delafloxacin (Fluoroquinolone Antibiotic); Sucralfate (Mucosal Protective Agent).
Sucralfate has 1 major-labeled pair vs Delafloxacin's 0. This page itself is in the minor band, not the major band.
0 major · 0 moderate · 2 minor · 2 total
- Other minor peers for Delafloxacin
- Zinc Sulfate
1 major · 1 moderate · 18 minor · 20 total
- Other minor peers for Sucralfate
- Warfarin
- Ketoconazole
- Ciprofloxacin
- Ofloxacin
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.