What the FDA labels say about taking them together
Ofloxacin and sucralfate
Sucralfate's FDA label of September 2, 2026 names ofloxacin in its drug interactions section; the ofloxacin labels PlainMeds reads (2) do not name sucralfate.
Check it at the source: the ofloxacin FDA label on DailyMed (effective July 18, 2024, Amneal Pharmaceuticals NY LLC); the sucralfate FDA label on DailyMed (effective September 2, 2026, Preferred Pharmaceuticals Inc.).
What does the ofloxacin label say about sucralfate?
Ofloxacin's label (effective July 18, 2024) and its 1 other brand-application label do not name sucralfate in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Ofloxacin), Amneal Pharmaceuticals NY LLC, effective July 18, 2024 (SPL set ba37e2a0-1bf7-41ca-bddd-35fcb77f87de), via openFDA; the full label on DailyMed
What does the sucralfate label say about ofloxacin?
Sucralfate label, drug interactionsIn all case studies to date (cimetidine, ciprofloxacin, digoxin, norfloxacin, ofloxacin, and ranitidine), dosing the concomitant medication 2 hours before sucralfate eliminated the interaction.
Source: FDA drug label (Sucralfate, NDA019183), Pacific Pharma, Inc., effective February 10, 2024 (SPL set 7407c58e-766f-4e93-a1bb-c77892ae0174), via openFDA
Source: FDA drug label (Sucralfate), NDA018333 (Abbvie), as published by Preferred Pharmaceuticals Inc., effective September 2, 2026 (SPL set 536b8c00-13ab-4397-a754-63a1c92bf883), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Ofloxacin | Sucralfate | |
|---|---|---|
| Labeled for | Bacterial infections | Acid reflux and ulcers |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $1.24 per mL 0.3% eye drops | $0.173 per tablet 1 g tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once