clindamycin vs colestipol
Side-by-side comparison of clindamycin and colestipol. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
No depressant effect on blood levels in humans was noted when colestipol hydrochloride was administered with any of the following drugs: aspirin, clindamycin, clofibrate, methyldopa, nicotinic acid (niacin), tolbutamide, phenytoin or warfarin.
Recommendation: You can take these medicines together as directed by your doctor. No special dose changes are typically required.
Cleocin
Colestid
Clindamycin phosphate topical lotion is an antibiotic medicine that you put on your skin. It helps treat acne.
Colestipol is a drug that helps lower cholesterol levels in your blood. It works by binding to bile acids in your intestine, which helps your body get rid of cholesterol.
This medicine treats acne. Acne is a skin condition that causes pimples and blemishes. Clindamycin helps to reduce the bacteria that cause acne.
Colestipol is used along with a healthy diet to lower high cholesterol levels, specifically LDL-C ('bad' cholesterol). It is for people who haven't been able to lower their cholesterol enough with diet alone. Lowering cholesterol can help prevent heart disease and stroke.
Clindamycin is an antibiotic. It works by stopping the growth of bacteria. This helps to reduce inflammation and clear up acne.
Colestipol is a bile acid sequestrant. It binds to bile acids in your intestines. This helps your body get rid of cholesterol, which lowers the amount of cholesterol in your blood.
- • Burning
- • Itching
- • Dryness
- • Redness
- • Peeling
- • Constipation
- • Abdominal discomfort (pain and cramping)
- • Intestinal gas (bloating and flatulence)
- • Indigestion and heartburn
- • Diarrhea and loose stools
- Allergic reaction to the medicine 2,314
- Diarrhea 1,877
- Skin rash 1,621
- Feeling sick to your stomach 1,615
- Pain 1,505
- Diarrhea 358
- Feeling sick to your stomach 221
- Feeling tired 210
- Headache 136
- Throwing up 125
Clindamycin, when taken orally or by injection, can cause severe diarrhea, bloody diarrhea, and colitis (inflammation of the colon). These problems have rarely been reported with topical clindamycin, but tell your doctor right away if you have diarrhea while using this medicine.
None
It is not known if clindamycin topical lotion can harm an unborn baby. Talk to your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
Tell your doctor if you are pregnant or plan to become pregnant. It is not known if colestipol can harm an unborn baby. Talk to your doctor about the risks and benefits of taking this medicine while pregnant or breastfeeding.
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How to Read This clindamycin vs colestipol Comparison
clindamycin is classified in the Lincosamide Antibiotic drug class, while colestipol sits within the Bile Acid Sequestrant class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, clindamycin has 8,932 submissions while colestipol has 1,050. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to colestipol does not seem to lower the levels of clindamycin in your blood or stop it from being absorbed.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between clindamycin and colestipol - always consult your physician or pharmacist first.
Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.