Bupropion · more major-labeled pairs than Brexpiprazole

SPL labels Bupropion + Brexpiprazole as minor; Bupropion 32 / Brexpiprazole 9 in that band.

Mechanism on file: Brexpiprazole does not change how the liver enzymes break down bupropion in the body.

FDA SPL severity: Minor

Bupropion

Full Bupropion label record

Norepinephrine-Dopamine Reuptake Inhibitor (NDRI)

Brexpiprazole

Full Brexpiprazole label record

Atypical Antipsychotic

Bupropion + Brexpiprazole · SPL mechanism field

Brexpiprazole does not change how the liver enzymes break down bupropion in the body.

Minor band excerpt · Bupropion with Brexpiprazole

Additionally, no dosage adjustment for substrates of CYP2D6 (e.g., dextromethorphan), CYP3A4 (e.g., lovastatin), CYP2B6 (e.g., bupropion), BCRP (e.g., rosuvastatin), or P-gp (e.g., fexofenadine) is required when administered concomitantly with REXULTI.

Bupropion · 1 major-labeled pairs (vs Brexpiprazole's 0)

View all Bupropion interactions →

FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.