What the FDA labels say about taking them together
Clarithromycin and quetiapine
Clarithromycin's FDA label of April 9, 2026 names quetiapine in its drug interactions section; the quetiapine labels PlainMeds reads (2) do not name clarithromycin. The clarithromycin label: “Careful monitoring of glucose is recommended. Use quetiapine and clarithromycin concomitantly with caution.”
Check it at the source: the clarithromycin FDA label on DailyMed (effective April 9, 2026, Solaris Pharma Corporation); the quetiapine FDA label on DailyMed (effective April 10, 2026, H2-Pharma, LLC).
What does the clarithromycin label say about quetiapine?
Clarithromycin label, drug interactionsPimozide Contraindicated Pimozide: [See Contraindications (4.2) ] Quetiapine Quetiapine: Quetiapine is a substrate for CYP3A4, which is inhibited by clarithromycin.
Clarithromycin label, warnings and precautionsCareful monitoring of glucose is recommended [see Drug Interactions (7) ]. Use quetiapine and clarithromycin concomitantly with caution.
Source: FDA drug label (Clarithromycin), Solaris Pharma Corporation, effective April 9, 2026 (SPL set 4d42821d-ce7a-7d64-e063-6294a90a0875), via openFDA; the full label on DailyMed
What does the quetiapine label say about clarithromycin?
Quetiapine's label (effective April 10, 2026) and its 1 other brand-application label do not name clarithromycin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (SEROQUEL), NDA020639 (Cheplapharm), as published by H2-Pharma, LLC, effective April 10, 2026 (SPL set 8ae62aaf-f8c5-417f-baac-0098369ca322), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Clarithromycin | Quetiapine | |
|---|---|---|
| Labeled for | Bacterial infections, Acid reflux and ulcers | Schizophrenia, Bipolar disorder, Depression |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.466 per tablet 500 mg tablet | $0.127 per tablet 300 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once