HIGH-VOLUME · SEX-BALANCED

semaglutide Side Effects

semaglutide (also sold as Ozempic, Wegovy) is HIGH-VOLUME in this FAERS book #102 of 524 by FAERS report count. Signature opener: SEX-BALANCED - 67% of sex-coded reports are female (43,872 F / 21,741 M).

Data updated 2026-05-15

72,117
FAERS reports

FAERS voluntary reports, 2013 to 2025. High volume tracks exposure and reporting culture; see methodology for de-dup rules.

semaglutide reporting skew - 67% of sex-coded reports are female (43,872 F / 21,741 M). Volume band HIGH-VOLUME #102 of 524 by FAERS report count; caseload CASELOAD.

High-report extract for semaglutide (Ozempic): 72,117 FAERS rows (2013-2025). Top named reactions: NAUSEA, VOMITING, DIARRHOEA. Outcome stamps DEATH-MARKED · HOSP-MID · SEX-BALANCED. FAERS is voluntary signal detection, not incidence.

Counts from the openFDA FAERS extract (2013–2025). Stamps CASELOAD · DEATH-MARKED · HOSP-MID · SEX-BALANCED.

NAUSEA leads 10,666 of 72,117 reports

NAUSEA
10,666
VOMITING
6,913
DIARRHOEA
6,093
DECREASED APPETITE
4,428
CONSTIPATION
4,344
WEIGHT DECREASED
3,931
FATIGUE
3,312
HEADACHE
3,156
BLOOD GLUCOSE INCREASED
2,752
ABDOMINAL PAIN UPPER
2,751
IMPAIRED GASTRIC EMPTYING
2,711
DIZZINESS
2,631
INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION
2,575
WEIGHT INCREASED
2,446
ABDOMINAL PAIN
2,233
DEHYDRATION
1,959
MALAISE
1,908

Who reports · age peak 45-64 (SEX-BALANCED)

Sex coding · SEX-BALANCED

Female 43,872 (67%)
Male 21,741 (33%)
Unknown 39

Age peak 45-64 (17,703 reports)

0-17 244 (1%)
18-44 6,424 (16%)
45-64 17,703 (44%)
65-74 10,577 (27%)
75+ 4,884 (12%)

FAERS filings rising toward 2025

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Reactions in Death Reports

Death appears on 1,213 reports (1.7% - MARKED). Reactions below co-occur in those rows only.

Reaction Reports
DEATH 384
NAUSEA 84
LACTIC ACIDOSIS 75
VOMITING 68
CARDIAC ARREST 63
DIARRHOEA 54
MYOCARDIAL INFARCTION 52
ACUTE KIDNEY INJURY 48
MULTIPLE ORGAN DYSFUNCTION SYNDROME 46
COMPLETED SUICIDE 45
PANCREATIC CARCINOMA 42
WEIGHT DECREASED 42
RENAL FAILURE 40
DECREASED APPETITE 39
ABDOMINAL PAIN 36
DEHYDRATION 32
SEPTIC SHOCK 32
DYSPNOEA 31

Reactions in Hospitalization Reports

Hospitalization mid-share (14,700, 20.4%). Co-reported reactions:

Reaction Reports
NAUSEA 2,470
VOMITING 2,446
DIARRHOEA 1,753
IMPAIRED GASTRIC EMPTYING 1,585
DEHYDRATION 1,249
CONSTIPATION 1,101
DECREASED APPETITE 1,051
ABDOMINAL PAIN 973
INTESTINAL OBSTRUCTION 686
ABDOMINAL PAIN UPPER 682
WEIGHT DECREASED 663
PANCREATITIS 618
ACUTE KIDNEY INJURY 612
FATIGUE 602
FALL 596
DIZZINESS 570
ASTHENIA 537
INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION 529
HEADACHE 509
How to read semaglutide FAERS figures (CASELOAD · DEATH-MARKED · HOSP-MID)

FAERS holds 72,117 voluntary reports linked to semaglutide (Ozempic, Wegovy, Rybelsus), 2013-2025. Death is listed on 1,213 (1.7%). Hospitalization appears on 14,700 (20.4%). Top co-reported indication: Product Used For Unknown Indication.

CASELOAD books overweight common drugs and loud reporting cultures; SEX-BALANCED is the page opener, not a per-patient risk.

Read with semaglutide

Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-MARKED · HOSP-MID stamps.