LOW-VOLUME · HOSP-HEAVY
alogliptin Side Effects
alogliptin (also sold as Nesina) is a LOW-VOLUME FAERS extract #418 of 524 by FAERS report count. Still opens on HOSP-HEAVY: 46.1% mention hospitalization (1,564 reports).
Data updated 2026-05-15
- 3,393
- FAERS reports
Thinner FAERS book - still a temporal association ledger, not proof of cause. Methodology.
alogliptin: 46.1% mention hospitalization (1,564 reports). Death stamp DEATH-HEAVY; volume band LOW-VOLUME #418 of 524 by FAERS report count.
Thinner FAERS extract for alogliptin (Nesina) (3,393 reports #418 of 524 by FAERS report count). 46.1% mention hospitalization (1,564 reports). Sparse books still carry named reaction rows when present; not medical advice.
Counts from the openFDA FAERS extract (2011–2025). Stamps SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
DIARRHOEA leads 134 of 3,393 reports
Who reports · age peak 75+ (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 75+ (885 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (356 reports, 10.5%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 71 |
| DIARRHOEA | 19 |
| PNEUMONIA | 19 |
| MALIGNANT NEOPLASM PROGRESSION | 18 |
| PYREXIA | 16 |
| INTERSTITIAL LUNG DISEASE | 15 |
| DECREASED APPETITE | 14 |
| CONDITION AGGRAVATED | 13 |
| SUDDEN DEATH | 13 |
| CARDIAC FAILURE | 12 |
| DISSEMINATED INTRAVASCULAR COAGULATION | 12 |
| PEMPHIGOID | 12 |
| VOMITING | 12 |
| CEREBRAL INFARCTION | 11 |
| SEPSIS | 11 |
| DEHYDRATION | 10 |
| PULMONARY ARTERIAL HYPERTENSION | 10 |
| MYOCARDIAL INFARCTION | 9 |
| NAUSEA | 9 |
| PLATELET COUNT DECREASED | 9 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (1,564, 46.1% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| ACUTE KIDNEY INJURY | 75 |
| PYREXIA | 62 |
| PNEUMONIA | 60 |
| VOMITING | 58 |
| DIARRHOEA | 57 |
| INTERSTITIAL LUNG DISEASE | 53 |
| DECREASED APPETITE | 51 |
| CEREBRAL INFARCTION | 48 |
| HYPOGLYCAEMIA | 46 |
| NAUSEA | 44 |
| FALL | 43 |
| BLOOD GLUCOSE INCREASED | 41 |
| CONDITION AGGRAVATED | 41 |
| DIABETIC KETOACIDOSIS | 41 |
| LACTIC ACIDOSIS | 40 |
| PEMPHIGOID | 40 |
| MALAISE | 39 |
| CONSTIPATION | 38 |
| PANCREATITIS ACUTE | 38 |
| RASH | 36 |
How to read alogliptin FAERS figures (SIGNAL · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 3,393 voluntary reports linked to alogliptin (Nesina), 2011-2025. Death is listed on 356 (10.5%). Hospitalization appears on 1,564 (46.1%). Top co-reported indication: Type 2 Diabetes Mellitus.
Sparse extract - named reactions and SEX-BALANCED skew still differ by drug; not a complete safety profile.
Read with alogliptin
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 3,396 FAERS cases (Δ 3 heavier vs alogliptin); DEATH-MARKED · HOSP-MID · FEMALE-LED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 3,350 FAERS cases (Δ 43 lighter vs alogliptin); DEATH-MARKED · HOSP-MID · MALE-LED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 3,344 FAERS cases (Δ 49 lighter vs alogliptin); DEATH-MARKED · HOSP-MID · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 3,330 FAERS cases (Δ 63 lighter vs alogliptin); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 51.6 pp vs alogliptin's DEATH-HEAVY): CASELOAD · HOSP-MID.
alogliptin stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload SIGNAL and the label guide.