HIGH-VOLUME · HOSP-HEAVY
digoxin Side Effects
digoxin (also sold as Lanoxin) is HIGH-VOLUME in this FAERS book #104 of 524 by FAERS report count. Signature opener: HOSP-HEAVY - 50.9% mention hospitalization (35,786 reports).
Data updated 2026-05-15
- 70,341
- FAERS reports
FAERS voluntary reports, 1999 to 2025. High volume tracks exposure and reporting culture; see methodology for de-dup rules.
digoxin: 50.9% mention hospitalization (35,786 reports). Death stamp DEATH-HEAVY; volume band HIGH-VOLUME #104 of 524 by FAERS report count.
High-report extract for digoxin (Lanoxin): 70,341 FAERS rows (1999-2025). Top named reactions: DYSPNOEA, NAUSEA, DIZZINESS. Outcome stamps DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED. FAERS is voluntary signal detection, not incidence.
Counts from the openFDA FAERS extract (1999–2025). Stamps CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
DYSPNOEA leads 6,065 of 70,341 reports
Who reports · age peak 75+ (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 75+ (23,317 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (13,641 reports, 19.4%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 3,384 |
| CARDIAC FAILURE CONGESTIVE | 1,100 |
| DYSPNOEA | 1,068 |
| ATRIAL FIBRILLATION | 993 |
| PNEUMONIA | 971 |
| RENAL FAILURE | 920 |
| CARDIAC ARREST | 908 |
| PAIN | 882 |
| HYPOTENSION | 870 |
| ASTHENIA | 789 |
| ECONOMIC PROBLEM | 765 |
| NAUSEA | 755 |
| RESPIRATORY FAILURE | 703 |
| INJURY | 687 |
| MYOCARDIAL INFARCTION | 682 |
| CARDIAC FAILURE | 667 |
| FALL | 644 |
| VOMITING | 608 |
| FATIGUE | 598 |
| ANXIETY | 595 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (35,786, 50.9% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| DYSPNOEA | 3,959 |
| ATRIAL FIBRILLATION | 3,014 |
| NAUSEA | 2,776 |
| CARDIAC FAILURE CONGESTIVE | 2,604 |
| ASTHENIA | 2,469 |
| DIZZINESS | 2,356 |
| PNEUMONIA | 2,318 |
| HYPOTENSION | 2,279 |
| VOMITING | 2,216 |
| FALL | 2,163 |
| DIARRHOEA | 2,090 |
| FATIGUE | 2,068 |
| BRADYCARDIA | 1,977 |
| DRUG INTERACTION | 1,813 |
| ANAEMIA | 1,805 |
| TOXICITY TO VARIOUS AGENTS | 1,800 |
| GASTROINTESTINAL HAEMORRHAGE | 1,692 |
| PAIN | 1,589 |
| CHEST PAIN | 1,519 |
| RENAL FAILURE | 1,470 |
How to read digoxin FAERS figures (CASELOAD · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 70,341 voluntary reports linked to digoxin (Lanoxin), 1999-2025. Death is listed on 13,641 (19.4%). Hospitalization appears on 35,786 (50.9%). Top co-reported indication: Product Used For Unknown Indication.
CASELOAD books overweight common drugs and loud reporting cultures; HOSP-HEAVY is the page opener, not a per-patient risk.
Read with digoxin
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 70,292 FAERS cases (Δ 49 lighter vs digoxin); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 70,203 FAERS cases (Δ 138 lighter vs digoxin); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 71,900 FAERS cases (Δ 1,559 heavier vs digoxin); DEATH-HEAVY · HOSP-MID · FEMALE-LED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 72,117 FAERS cases (Δ 1,776 heavier vs digoxin); DEATH-MARKED · HOSP-MID · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 42.7 pp vs digoxin's DEATH-HEAVY): CASELOAD · HOSP-MID.
digoxin stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload CASELOAD and the label guide.