HIGH-VOLUME · FEMALE-LED

cetirizine Side Effects

cetirizine (also sold as Zyrtec) is HIGH-VOLUME in this FAERS book #100 of 524 by FAERS report count. Signature opener: FEMALE-LED - 71% of sex-coded reports are female (44,738 F / 18,377 M).

Data updated 2026-05-15

72,729
FAERS reports

FAERS voluntary reports, 2004 to 2025. High volume tracks exposure and reporting culture; see methodology for de-dup rules.

cetirizine reporting skew - 71% of sex-coded reports are female (44,738 F / 18,377 M). Volume band HIGH-VOLUME #100 of 524 by FAERS report count; caseload CASELOAD.

High-report extract for cetirizine (Zyrtec): 72,729 FAERS rows (2004-2025). Top named reactions: FATIGUE, PAIN, RASH. Outcome stamps DEATH-HEAVY · HOSP-HEAVY · FEMALE-LED. FAERS is voluntary signal detection, not incidence.

Counts from the openFDA FAERS extract (2004–2025). Stamps CASELOAD · DEATH-HEAVY · HOSP-HEAVY · FEMALE-LED.

FATIGUE leads 12,861 of 72,729 reports

FATIGUE
12,861
PAIN
12,124
RASH
9,771
ABDOMINAL DISCOMFORT
9,317
ALOPECIA
9,237
RHEUMATOID ARTHRITIS
8,675
SYSTEMIC LUPUS ERYTHEMATOSUS
8,466
PEMPHIGUS
8,274
SWELLING
7,934
HYPERSENSITIVITY
7,746
GLOSSODYNIA
7,743
PRURITUS
7,514
ARTHRALGIA
7,475
HEADACHE
7,470
DYSPNOEA
7,156
JOINT SWELLING
6,995
INFUSION RELATED REACTION
6,954
HAND DEFORMITY
6,762

FEMALE-LED reporters · age peak 18-44

Female-led reporters (71% of sex-coded rows)

Female 44,738 (71%)
Male 18,377 (29%)
Unknown 60

Age peak 18-44 (15,430 reports)

0-17 4,644 (10%)
18-44 15,430 (32%)
45-64 14,527 (30%)
65-74 7,743 (16%)
75+ 5,859 (12%)

FAERS filings rising toward 2025

2004 2025

Reactions in Death Reports

Death-mentioned subset is HEAVY here (7,810 reports, 10.7%). Top co-reported reactions in that subset - voluntary, not causal.

Reaction Reports
FATIGUE 2,132
SYSTEMIC LUPUS ERYTHEMATOSUS 2,129
RASH 2,113
RHEUMATOID ARTHRITIS 2,110
GENERAL PHYSICAL HEALTH DETERIORATION 2,096
HYPERTENSION 2,093
INFUSION RELATED REACTION 2,089
HEPATIC ENZYME INCREASED 2,074
TYPE 2 DIABETES MELLITUS 2,070
GLOSSODYNIA 2,066
HAND DEFORMITY 2,037
DUODENAL ULCER PERFORATION 2,023
JOINT SWELLING 2,013
HELICOBACTER INFECTION 1,971
FIBROMYALGIA 1,969
HYPOAESTHESIA 1,966
SYNOVITIS 1,956
WOUND 1,954
PSORIATIC ARTHROPATHY 1,947

Reactions in Hospitalization Reports

Hospitalization is HEAVY (22,963, 31.6% of the book). Top reactions in those rows:

Reaction Reports
FATIGUE 4,029
PAIN 3,617
DYSPNOEA 3,442
RASH 3,316
ABDOMINAL DISCOMFORT 3,230
PYREXIA 3,190
ARTHRALGIA 3,148
MALAISE 3,023
NAUSEA 2,989
DIARRHOEA 2,982
VOMITING 2,980
SWELLING 2,951
SYSTEMIC LUPUS ERYTHEMATOSUS 2,936
ALOPECIA 2,930
INFUSION RELATED REACTION 2,901
RHEUMATOID ARTHRITIS 2,886
HEADACHE 2,881
HYPERSENSITIVITY 2,808
How to read cetirizine FAERS figures (CASELOAD · DEATH-HEAVY · HOSP-HEAVY)

FAERS holds 72,729 voluntary reports linked to cetirizine (Zyrtec), 2004-2025. Death is listed on 7,810 (10.7%). Hospitalization appears on 22,963 (31.6%). Top co-reported indication: Product Used For Unknown Indication.

CASELOAD books overweight common drugs and loud reporting cultures; FEMALE-LED is the page opener, not a per-patient risk.

Read with cetirizine

Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.