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bromocriptine Side Effects

Also known as: Cycloset

Analysis of 637 adverse event reports submitted to the FDA from 2003 to 2025.

Total Reports

637

Death-Related

30

4.7% of reports

Hospitalizations

231

36.3% of reports

Top Indication

Product Used For Unknown Indication

Most Reported Adverse Reactions

NAUSEA
46
DRUG INEFFECTIVE
36
HEADACHE
35
VOMITING
33
DIZZINESS
31
PYREXIA
29
FATIGUE
28
DRUG EXPOSURE DURING PREGNANCY
25
NEUROLEPTIC MALIGNANT SYNDROME
24
TREMOR
22
SOMNOLENCE
20
DIARRHOEA
19
DYSPNOEA
19
BLOOD CREATINE PHOSPHOKINASE INCREASED
18
HYPOTENSION
18
MALAISE
18
OFF LABEL USE
17
BLOOD GLUCOSE INCREASED
16
CONDITION AGGRAVATED
16
DRUG INTERACTION
16

Who Reports Side Effects

Gender Distribution

Female 316 (55%)
Male 260 (45%)
Unknown 2

Age Distribution

0-17 18 (4%)
18-44 165 (38%)
45-64 122 (28%)
65-74 79 (18%)
75+ 48 (11%)

Reporting Trend by Year

2003 2025

Reactions in Death Reports

Top reactions reported in 30 reports where death was an outcome. These are voluntarily reported and do not establish causation.

Reaction Reports
DEATH 7
PNEUMONIA 4
VENTRICULAR FIBRILLATION 4
AGITATION 3
ARRHYTHMIA 3
CARDIAC ARREST 3
CARDIO-RESPIRATORY ARREST 3
DRUG EXPOSURE DURING PREGNANCY 3
DRUG INTERACTION 3
LETHARGY 3
PSYCHOTIC DISORDER 3
RESPIRATORY ARREST 3
ANOXIC ENCEPHALOPATHY 2
BLOOD CREATINE PHOSPHOKINASE INCREASED 2
CARDIAC FAILURE 2
DYSPNOEA 2
LOSS OF CONSCIOUSNESS 2
MYOCARDIAL INFARCTION 2
PARALYSIS 2
PREMATURE LABOUR 2

Reactions in Hospitalization Reports

Top reactions in 231 reports where hospitalization was an outcome.

Reaction Reports
NEUROLEPTIC MALIGNANT SYNDROME 22
PYREXIA 17
DYSPNOEA 14
VOMITING 14
MUSCLE RIGIDITY 13
TREMOR 13
BLOOD CREATINE PHOSPHOKINASE INCREASED 12
DIARRHOEA 12
DRUG INTOLERANCE 12
NAUSEA 12
DRUG INEFFECTIVE 11
HALLUCINATION, VISUAL 11
HEADACHE 11
AGITATION 10
CONFUSIONAL STATE 10
CEREBROVASCULAR ACCIDENT 9
CONDITION AGGRAVATED 9
DIZZINESS 9
DRUG EXPOSURE DURING PREGNANCY 9
HALLUCINATION 9

Nearby — Related Medications

Compare bromocriptine vs acarbose →

What the FAERS Data Reveals About bromocriptine Side Effects

The FDA Adverse Event Reporting System (FAERS) contains 637 voluntary reports linked to bromocriptine and its brand equivalents (Cycloset), spanning 2003 through 2025. Of those, 30 (4.7%) listed death as an outcome and 231 (36.3%) involved hospitalization. The most common indication reported alongside adverse events was Product Used For Unknown Indication.

Demographic breakdowns help contextualize who is being exposed to the drug. Of reports with known sex, 55% were female and 45% male; age distribution skews toward 18-44, with 165 reports in that bracket. The single most reported reaction is nausea with 46 submissions, followed by drug ineffective and headache.

FAERS is a signal-detection tool, not a scorecard. Reports are voluntary, and a single case may list multiple suspect drugs, so numbers above should not be read as incidence rates or per-patient risk. Widely prescribed drugs naturally accumulate more reports than niche therapies even when individual risk is low. These aggregates are useful for spotting patterns that merit further pharmacovigilance, not for choosing between medications. This page is for educational reference only and is not medical advice — speak with a licensed clinician about any side-effect concerns.