HIGH-VOLUME · HOSP-HEAVY
metronidazole Side Effects
metronidazole (also sold as Flagyl) is HIGH-VOLUME in this FAERS book #116 of 524 by FAERS report count. Signature opener: HOSP-HEAVY - 41.9% mention hospitalization (26,693 reports).
Data updated 2026-05-15
- 63,731
- FAERS reports
FAERS voluntary reports, 1999 to 2025. High volume tracks exposure and reporting culture; see methodology for de-dup rules.
metronidazole: 41.9% mention hospitalization (26,693 reports). Death stamp DEATH-HEAVY; volume band HIGH-VOLUME #116 of 524 by FAERS report count.
High-report extract for metronidazole (Flagyl): 63,731 FAERS rows (1999-2025). Top named reactions: NAUSEA, DIARRHOEA, VOMITING. Outcome stamps DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED. FAERS is voluntary signal detection, not incidence.
Counts from the openFDA FAERS extract (1999–2025). Stamps CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
NAUSEA leads 4,693 of 63,731 reports
Who reports · age peak 45-64 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 45-64 (14,581 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (6,727 reports, 10.6%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 1,067 |
| SEPSIS | 823 |
| MULTIPLE ORGAN DYSFUNCTION SYNDROME | 639 |
| SEPTIC SHOCK | 523 |
| NAUSEA | 521 |
| VOMITING | 507 |
| ABDOMINAL PAIN | 506 |
| GENERAL PHYSICAL HEALTH DETERIORATION | 492 |
| PNEUMONIA | 472 |
| RENAL FAILURE | 467 |
| PYREXIA | 461 |
| CONDITION AGGRAVATED | 445 |
| ANAEMIA | 439 |
| DYSPNOEA | 418 |
| DIARRHOEA | 394 |
| RESPIRATORY FAILURE | 375 |
| ASCITES | 374 |
| ABDOMINAL DISTENSION | 356 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (26,693, 41.9% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| DIARRHOEA | 2,191 |
| NAUSEA | 2,138 |
| PYREXIA | 2,084 |
| VOMITING | 1,845 |
| ABDOMINAL PAIN | 1,842 |
| PAIN | 1,700 |
| DYSPNOEA | 1,303 |
| ANAEMIA | 1,248 |
| FATIGUE | 1,167 |
| ACUTE KIDNEY INJURY | 1,103 |
| WEIGHT DECREASED | 1,087 |
| ASTHENIA | 1,080 |
| HEADACHE | 1,080 |
| CONDITION AGGRAVATED | 1,062 |
| MALAISE | 1,058 |
| PNEUMONIA | 1,027 |
| SEPSIS | 996 |
| DIZZINESS | 834 |
How to read metronidazole FAERS figures (CASELOAD · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 63,731 voluntary reports linked to metronidazole (Flagyl), 1999-2025. Death is listed on 6,727 (10.6%). Hospitalization appears on 26,693 (41.9%). Top co-reported indication: Product Used For Unknown Indication.
CASELOAD books overweight common drugs and loud reporting cultures; HOSP-HEAVY is the page opener, not a per-patient risk.
Read with metronidazole
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 63,762 FAERS cases (Δ 31 heavier vs metronidazole); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 63,536 FAERS cases (Δ 195 lighter vs metronidazole); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 64,119 FAERS cases (Δ 388 heavier vs metronidazole); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 64,404 FAERS cases (Δ 673 heavier vs metronidazole); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 51.6 pp vs metronidazole's DEATH-HEAVY): CASELOAD · HOSP-MID.
metronidazole stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload CASELOAD and the label guide.