HIGH-VOLUME · HOSP-HEAVY
doxycycline hyclate Side Effects
doxycycline hyclate (also sold as Doryx MPC) is HIGH-VOLUME in this FAERS book #115 of 524 by FAERS report count. Signature opener: HOSP-HEAVY - 32.3% mention hospitalization (20,575 reports).
Data updated 2026-05-15
- 63,762
- FAERS reports
FAERS voluntary reports, 2003 to 2025. High volume tracks exposure and reporting culture; see methodology for de-dup rules.
doxycycline hyclate: 32.3% mention hospitalization (20,575 reports). Death stamp DEATH-HEAVY; volume band HIGH-VOLUME #115 of 524 by FAERS report count.
High-report extract for doxycycline hyclate (Doryx MPC): 63,762 FAERS rows (2003-2025). Top named reactions: NAUSEA, FATIGUE, RASH. Outcome stamps DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED. FAERS is voluntary signal detection, not incidence.
Counts from the openFDA FAERS extract (2003–2025). Stamps CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
NAUSEA leads 4,733 of 63,762 reports
Who reports · age peak 45-64 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 45-64 (14,257 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (6,312 reports, 9.9%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 1,422 |
| FATIGUE | 1,050 |
| HYPERTENSION | 961 |
| HYPOAESTHESIA | 956 |
| GENERAL PHYSICAL HEALTH DETERIORATION | 946 |
| VOMITING | 941 |
| HYPERSENSITIVITY | 921 |
| RASH | 921 |
| GLOSSODYNIA | 916 |
| PYREXIA | 915 |
| IMPAIRED HEALING | 911 |
| TYPE 2 DIABETES MELLITUS | 906 |
| HELICOBACTER INFECTION | 905 |
| INJURY | 905 |
| HAND DEFORMITY | 901 |
| INFECTION | 899 |
| FIBROMYALGIA | 879 |
| HEPATIC ENZYME INCREASED | 874 |
| JOINT SWELLING | 871 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (20,575, 32.3% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| DYSPNOEA | 2,216 |
| FATIGUE | 2,066 |
| NAUSEA | 1,901 |
| VOMITING | 1,864 |
| PAIN | 1,842 |
| PNEUMONIA | 1,829 |
| DIARRHOEA | 1,826 |
| PYREXIA | 1,740 |
| RASH | 1,687 |
| HEADACHE | 1,557 |
| MALAISE | 1,467 |
| CONDITION AGGRAVATED | 1,417 |
| HYPERTENSION | 1,370 |
| ARTHRALGIA | 1,366 |
| INFECTION | 1,331 |
| ASTHENIA | 1,303 |
| ANXIETY | 1,274 |
| DIZZINESS | 1,256 |
How to read doxycycline hyclate FAERS figures (CASELOAD · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 63,762 voluntary reports linked to doxycycline hyclate (Doryx MPC), 2003-2025. Death is listed on 6,312 (9.9%). Hospitalization appears on 20,575 (32.3%). Top co-reported indication: Product Used For Unknown Indication.
CASELOAD books overweight common drugs and loud reporting cultures; HOSP-HEAVY is the page opener, not a per-patient risk.
Read with doxycycline hyclate
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 63,731 FAERS cases (Δ 31 lighter vs doxycycline hyclate); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 63,536 FAERS cases (Δ 226 lighter vs doxycycline hyclate); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 64,119 FAERS cases (Δ 357 heavier vs doxycycline hyclate); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 64,404 FAERS cases (Δ 642 heavier vs doxycycline hyclate); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 52.2 pp vs doxycycline hyclate's DEATH-HEAVY): CASELOAD · HOSP-MID.
doxycycline hyclate stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload CASELOAD and the label guide.