Over-the-counter medicine
Calcium carbonate
Calcium carbonate is an over-the-counter medicine. No generic is listed; pharmacies paid $0.0315 per tablet (Antacid ex-str 750 mg tablet chewable) in the October 7, 2026 NADAC survey.
- No generic listed
- Over the counter
Check it at the source: the calcium carbonate FDA label on DailyMed (effective December 5, 2024); every calcium carbonate label on DailyMed.
Highlights of the record
FDA label of December 5, 2024; NDC Directory, Drugs@FDA and Orange Book, October 8, 2026; NADAC October 7, 2026
Used for
From the label: indications and usagerelieves
heartburn
acid indigestion
sour stomach
upset stomach associated with these symptoms
Forms and strengths
- 55 mg
- 90 mg
- 200.4 mg
- 250 mg
- 400 mg
- 420 mg
- 500 mg
- 648 mg
- 750 mg
- 1000 mg
- 1177 mg
- 1250 mg
Chewable tablet; tablet; lozenge; suspension; chewable bar.
On the market
- Generic approvals
- No generic approved
- Labelers listed (NDC)
- 157 of which 0 under generic applications, 0 under brand applications, repackagers included
Supply and safety
- Pharmacy cost (NADAC)
- $0.0315 per tablet Antacid ex-str 750 mg tablet chewable
- Shortage (FDA)
- No current entry
- Recalls by its makers (FDA)
- 1 since 2013 0 Class I among all firms' recalls; latest June 7, 2022; 20 more by firms not listed as its makers
- FAERS reports
- 66,848 through July 30, 2026
What is calcium carbonate used for?
From the label: indications and usagerelieves
heartburn
acid indigestion
sour stomach
upset stomach associated with these symptoms
Conditions named in the indications of calcium carbonate's FDA labels, with every medicine labeled for each:
From other calcium carbonate labelsAcid reflux and ulcers: Temporarily relieves heartburn sour stomach acid indigestion upset stomach
Source: FDA drug label (TUMS EX), Haleon US Holdings LLC, effective December 5, 2024 (SPL set 593a0494-d669-4bcf-8412-b92645b2d76c), via openFDA; the full label on DailyMed
Is there a generic for calcium carbonate?
No generic calcium carbonate is approved (Drugs@FDA, October 8, 2026).
Source: Drugs@FDA, FDA NDC Directory and the Orange Book (openFDA bulk files, October 8, 2026)
What do pharmacies pay for calcium carbonate?
In CMS's NADAC survey of October 7, 2026, pharmacies paid $0.0315 per tablet (Antacid ex-str 750 mg tablet chewable), about the same as a year earlier. The chart's scale runs from the lowest to the highest price shown, not from zero. NADAC is what retail pharmacies paid their wholesalers, per unit, in CMS's monthly survey; what a patient pays depends on insurance and the pharmacy.
- Antacid ex-str 750 mg tablet chewable (generic)
| Strength and form | Brand or generic | Pharmacy cost | 30 tablets, or one pen or vial | 12-month change |
|---|---|---|---|---|
| Antacid 500 mg chewable tablet | Generic | $0.0169 per tablet | $0.506 | -2% |
| Antacid 500 mg chewable tablet | Generic | $0.0169 per tablet | $0.506 | -2% |
| Antacid 750 mg chewable tablet | Generic | $0.0315 per tablet | $0.946 | -0.8% |
| Antacid ex-str 750 mg tablet chewable | Generic | $0.0315 per tablet | $0.946 | -0.8% |
| Antacid ultra str 1,000 mg chw | Generic | $0.037 per unit | n/a | +3% |
| Antacid ultra tablet chewable | Generic | $0.037 per tablet | $1.11 | +3% |
| Antacid xtra strength chewable tablet | Generic | $0.0315 per tablet | $0.946 | -0.8% |
| Cal-gest 500 mg tablet chewable | Generic | $0.0169 per tablet | $0.506 | -2% |
| Calcium antacid 500 mg chw tablet | Generic | $0.0169 per tablet | $0.506 | -2% |
| Calcium antacid 750 mg chewable tablet | Generic | $0.0315 per tablet | $0.946 | -0.8% |
| Calcium carb 1,250 mg/5 mL sus | Generic | $0.0204 per mL | n/a | +0.9% |
| Calcium carbonate 648 mg tablet | Generic | $0.0081 per tablet | $0.242 | +2% |
| Ft antacid 500 mg chewable tablet | Generic | $0.0169 per tablet | $0.506 | -2% |
| Ft antacid ex-str 750 mg chewable | Generic | $0.0315 per unit | n/a | -0.8% |
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
Has calcium carbonate been recalled?
The FDA's Enforcement Report lists 21 recalls naming calcium carbonate since 2013: 0 Class I (the most serious), 20 Class II, 1 Class III; 14 still ongoing. 20 of them are by firms that FDA's NDC Directory does not list as a maker of calcium carbonate and that hold no application for it in Drugs@FDA, such as compounding pharmacies or bulk-ingredient suppliers; the recall notice names the product recalled. A recall names products and lots, not every product of the medicine.
| Started | Class | Company | Reason |
|---|---|---|---|
| May 28, 2026 | Class II | Guardian Drug Co. Inc. not a listed maker | Presence of foreign substance: small metallic particles in chewable tablets. |
| November 11, 2024 | Class II | Safecor Health, LLC not a listed maker | cGMP Deviations: Observations were made that some blister card-foils were separating from the blister cavity. |
| December 2, 2022 | Class II | GlaxoSmithKline Consumer Healthcare Holdings LLC not a listed maker | Presence of Foreign Substance: The foreign material is primarily comprised of glass mineral wool. |
| June 7, 2022 | Class II | Plastikon Healthcare LLC | CGMP Deviations: products manufactured under conditions which reflect manufacturing processes that were not adequately controlled. |
| July 7, 2016 | Class II | Safecor Health, LLC not a listed maker | CGMP Deviations |
| July 18, 2013 | Class III | GlaxoSmithKline, LLC. not a listed maker | Presence of Foreign Tablets/Capsules: Product labeled TUMS Ultra Assorted Berries 1000mg Chewable tables, may contain EX TUMS Assorted Berries 750mg tablets |
Source: FDA Enforcement Report (drug recalls) via openFDA, through October 8, 2026
What does the calcium carbonate label say about other medicines?
The calcium carbonate label names no other medicine on this site. The labels of 10 other medicines name calcium carbonate. The sentences are the labels' own; a label lists what its studies and reports found, not every interaction.
Other labels that name calcium carbonate
Source: FDA drug label (TUMS EX), Haleon US Holdings LLC, effective December 5, 2024 (SPL set 593a0494-d669-4bcf-8412-b92645b2d76c), via openFDA; the full label on DailyMed
What do FAERS reports show for calcium carbonate?
The FDA Adverse Event Reporting System holds 66,848 reports that list calcium carbonate among the medicines taken, through July 30, 2026, each a report of something that happened, not proof the medicine caused it; 9,276 are coded as a death and 28,152 as a hospital stay. Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is.
Reports received each year
The most reported reactions
Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026
What else is labeled for the same conditions as calcium carbonate?
20 other medicines are given the same way (oral) and in the same FDA class as calcium carbonate or labeled mainly for the same use (acid reflux and ulcers), the same class first. Acid reflux and ulcers lists all 27 medicines labeled for it, by any route. The first 8 are below. They are listed as records, not as substitutes: whether one can replace another is a prescriber's decision.
| Medicine | Shared indication | Generic labelers (oral) | Pharmacy cost | Shortage |
|---|---|---|---|---|
| Omeprazole | Acid reflux and ulcers | 121 labelers | $0.0295 per capsule 20 mg capsule | A presentation being discontinued |
| Famotidine | Acid reflux and ulcers | 144 labelers | $0.0289 per tablet 20 mg tablet | No current entry |
| Esomeprazole | Acid reflux and ulcers | 117 labelers | $0.145 per capsule 20 mg capsule | No current entry |
| Pantoprazole | Acid reflux and ulcers | 52 labelers | $0.0358 per tablet 40 mg tablet | No current entry |
| Lansoprazole | Acid reflux and ulcers | 59 labelers | $0.106 per capsule 30 mg capsule | No current entry |
| Sucralfate | Acid reflux and ulcers | 43 labelers | $0.173 per tablet 1 g tablet | No current entry |
| Metoclopramide | Acid reflux and ulcers | 28 labelers | $0.0439 per tablet 10 mg tablet | No current entry |
| Sodium bicarbonate | Acid reflux and ulcers | none listed | $0.0128 per tablet 650 mg tablet | In shortage |
Every medicine labeled for the same conditions as calcium carbonate
Source: FDA drug labels (indications), NDC Directory, NADAC of October 7, 2026, FDA shortages (October 8, 2026)
How does calcium carbonate compare with medicines for the same use?
5 side-by-side pages set calcium carbonate beside a medicine whose label shares a use: approvals, generics, pharmacy cost, warnings and supply.
What next?
- Alternatives to calcium carbonate
- 20 medicines for the same use
- Calcium carbonate side effects
- the label's list beside FAERS reports
- Check an interaction
- what two or more labels say about each other