HIGH-VOLUME · BLOOD GLUCOSE INCREASED
insulin lispro Side Effects
insulin lispro (also sold as Humalog) is HIGH-VOLUME in this FAERS book #48 of 524 by FAERS report count. Signature opener: BLOOD GLUCOSE INCREASED - BLOOD GLUCOSE INCREASED leads at 38,180 reports (28.5% of the book).
Data updated 2026-05-15
- 134,198
- FAERS reports
FAERS voluntary reports, 2004 to 2025. High volume tracks exposure and reporting culture; see methodology for de-dup rules.
Among 134,198 FAERS reports for insulin lispro, BLOOD GLUCOSE INCREASED is the most-reported reaction (38,180). Volume band HIGH-VOLUME #48 of 524 by FAERS report count.
High-report extract for insulin lispro (Humalog): 134,198 FAERS rows (2004-2025). Top named reactions: BLOOD GLUCOSE INCREASED, INCORRECT DOSE ADMINISTERED, BLOOD GLUCOSE DECREASED. Outcome stamps DEATH-MARKED · HOSP-MID · SEX-BALANCED. FAERS is voluntary signal detection, not incidence.
Counts from the openFDA FAERS extract (2004–2025). Stamps MEGA-CASE · DEATH-MARKED · HOSP-MID · SEX-BALANCED.
BLOOD GLUCOSE INCREASED leads 38,180 of 134,198 reports
Who reports · age peak 45-64 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 45-64 (25,559 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death appears on 5,906 reports (4.4% - MARKED). Reactions below co-occur in those rows only.
| Reaction | Reports |
|---|---|
| DEATH | 2,351 |
| PNEUMONIA | 343 |
| RENAL FAILURE | 337 |
| ACUTE KIDNEY INJURY | 321 |
| DYSPNOEA | 268 |
| SEPSIS | 249 |
| MYOCARDIAL INFARCTION | 245 |
| RESPIRATORY FAILURE | 224 |
| CARDIAC ARREST | 211 |
| CHRONIC KIDNEY DISEASE | 189 |
| CARDIAC FAILURE CONGESTIVE | 185 |
| NAUSEA | 181 |
| ANAEMIA | 176 |
| ASTHENIA | 167 |
| FALL | 166 |
| DIARRHOEA | 165 |
| HYPOTENSION | 162 |
| FATIGUE | 157 |
| VOMITING | 157 |
Reactions in Hospitalization Reports
Hospitalization mid-share (33,389, 24.9%). Co-reported reactions:
| Reaction | Reports |
|---|---|
| BLOOD GLUCOSE INCREASED | 5,579 |
| FALL | 2,085 |
| BLOOD GLUCOSE DECREASED | 1,931 |
| PNEUMONIA | 1,872 |
| HYPOGLYCAEMIA | 1,863 |
| DYSPNOEA | 1,830 |
| NAUSEA | 1,767 |
| VOMITING | 1,738 |
| DIABETIC KETOACIDOSIS | 1,475 |
| CEREBROVASCULAR ACCIDENT | 1,396 |
| FATIGUE | 1,393 |
| DIARRHOEA | 1,387 |
| ASTHENIA | 1,354 |
| MALAISE | 1,323 |
| ACUTE KIDNEY INJURY | 1,232 |
| PAIN | 1,168 |
| WEIGHT DECREASED | 1,143 |
| MYOCARDIAL INFARCTION | 1,120 |
| HEADACHE | 1,056 |
How to read insulin lispro FAERS figures (MEGA-CASE · DEATH-MARKED · HOSP-MID)
FAERS holds 134,198 voluntary reports linked to insulin lispro (Humalog), 2004-2025. Death is listed on 5,906 (4.4%). Hospitalization appears on 33,389 (24.9%). Top co-reported indication: Product Used For Unknown Indication.
MEGA-CASE books overweight common drugs and loud reporting cultures; BLOOD GLUCOSE INCREASED is the page opener, not a per-patient risk.
Read with insulin lispro
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-MARKED · HOSP-MID stamps.
ABS(total_reports) peer at 133,996 FAERS cases (Δ 202 lighter vs insulin lispro); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's MEGA-CASE · DEATH-MARKED · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 134,536 FAERS cases (Δ 338 heavier vs insulin lispro); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's MEGA-CASE · DEATH-MARKED · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 133,513 FAERS cases (Δ 685 lighter vs insulin lispro); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's MEGA-CASE · DEATH-MARKED · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 133,227 FAERS cases (Δ 971 lighter vs insulin lispro); DEATH-HEAVY · HOSP-MID · FEMALE-LED vs this page's MEGA-CASE · DEATH-MARKED · HOSP-MID · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 57.7 pp vs insulin lispro's DEATH-MARKED): CASELOAD · HOSP-MID.
insulin lispro sits in MEGA-CASE; high report volume tracks exposure and reporting culture more than per-patient risk. Methodology states the de-dup rules.