Skip to main content

FDA pharmacologic class

NSAIDs (nonsteroidal anti-inflammatory drugs)

21 medicines are in FDA's class of nonsteroidal anti-inflammatory drugs (NSAIDs): ibuprofen (Advil), naproxen (Aleve), diclofenac (Voltaren), celecoxib (Celebrex), ketorolac (Acular), meloxicam (Qamzova), etodolac, indomethacin (Indocin) and 13 more; 23 combination products also contain one. 37 of the 44 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is meloxicam 7.5 mg tablet at $0.0166 per tablet (NADAC).

Which medicines are nsaids?

Recalls: FDA enforcement reports, 2012 on
MedicineBrand namesGeneric labelers (all forms)Pharmacy costBoxed warningShortageRecalls since 2012
IbuprofenAdvil, Motrin, Caldolor245 labelers$0.0573 per tablet 800 mg tabletYesNo current entry40
NaproxenAleve, Naprelan, Bayer139 labelers$0.0565 per tablet 500 mg tabletYesNo current entry8
DiclofenacVoltaren, Zipsor, Cambia149 labelers$0.0619 per tablet 75 mg tabletYesA presentation being discontinued6
CelecoxibCelebrex, Vyscoxa63 labelers$0.0762 per capsule 200 mg capsuleYesNo current entry2
KetorolacAcular, Sprix, Acuvail60 labelers$1.02 per mL 30 mg/mL vialYesIn shortage24
Acetaminophen and aspirin and caffeineExcedrin39 labelers$0.0648 per unit 250-250-65 mg cpltNoNo current entry3
MeloxicamQamzova, Xifyrm, Zybic43 labelers$0.0166 per tablet 7.5 mg tabletYesNo current entry3
Etodolacnone listed30 labelers$0.262 per tablet 400 mg tabletYesNo current entry0
IndomethacinIndocin31 labelers$0.210 per capsule 75 mg capsuleYesNo current entry9
Acetaminophen and ibuprofenCombogesic47 labelers$0.107 per unit 250-125 mgYesNo current entry1
NabumetoneRelafen28 labelers$0.128 per tablet 500 mg tabletYesNo current entry1
Diphenhydramine and ibuprofenAdvil39 labelers$0.131 per unit Gs ibuprofen pm capletNoNo current entry1
Diclofenac and misoprostolArthrotec10 labelers$0.665 per tablet 50-0.2 mg tabletYesNo current entry7
Piroxicamnone listed10 labelers$0.215 per capsule 20 mg capsuleYesNo current entry0
Esomeprazole and naproxennone listed10 labelers$1.96 per unit 500-20 mgYesNo current entry0
Famotidine and ibuprofennone listed16 labelers$0.714 per unit 800-26.6 mgYesNo current entry1
Diphenhydramine and naproxenAleve17 labelersn/aNoNo current entry0
BromfenacProlensa, Bromsite9 labelers$13.25 per mL 0.07% eye drpNoNo current entry4
Sulindacnone listed7 labelers$0.189 per tablet 150 mg tabletYesNo current entry1
Ibuprofen and pseudoephedrineAdvil9 labelersn/aNoNo current entry0
Naproxen and pseudoephedrinenone listed10 labelers$0.244 per unit 220-120 mgNoNo current entry0
Fenoprofennone listed6 labelersn/aYesNo current entry0
OxaprozinCoxanto7 labelers$0.475 per tablet 600 mg tabletYesNo current entry0
Aspirin and dipyridamolenone listed9 labelers$0.559 per unit 25-200 mgNoNo current entry2
FlurbiprofenLurbiro7 labelers$9.83 per mL 0.03% eye dropNoNo current entry0
DiflunisalDolobid6 labelers$1.06 per tablet 500 mg tabletYesNo current entry0
KetoprofenOrudis5 labelers$6.46 per capsule 200 mg capsuleYesNo current entry0
Mefenamic acidnone listed6 labelers$0.948 per capsule 250 mg capsuleYesNo current entry2
Tolmetinnone listed5 labelersn/aYesNo current entry0
Aspirin and butalbital and caffeinenone listed5 labelers$0.948 per capsule 50-325-40 mg capsuleNoNo current entry0
Aspirin and caffeine and orphenadrineNorgesic, Orphengesic3 labelersn/aNoNo current entry0
Hydrocodone and ibuprofennone listed2 labelers$0.487 per unit 7.5-200YesNo current entry0
Ibuprofen and phenylephrineAdvil3 labelersn/aNoNo current entry0
Naproxen and sumatriptanTreximet3 labelers$10.46 per unit 85-500 mgYesNo current entry0
Aspirin, butalbital, caffeine and codeinenone listed4 labelers$1.00 per capsule Ascomp with codeine capsuleYesNo current entry0
Chlorpheniramine and ibuprofen and phenylephrineAdvilnone listedn/aNoNo current entry1
Ibuprofen lysineNeoprofen1 labelern/aNoNo current entry1
NepafenacIlevro, Nevanacnone listed$121.14 per mL 0.3% eye dropsNoNo current entry0
Bupivacaine and meloxicamZynrelefnone listedn/aYesNo current entry1
Ketorolac and phenylephrineOmidrianone listedn/aNoNo current entry0
Aspirin and oxycodonenone listed1 labelern/aYesNo current entry0
Chlorpheniramine and ibuprofen and pseudoephedrineAdvilnone listedn/aNoNo current entry0
Dextromethorphan and guaifenesin and naproxenMucinexnone listedn/aNoNo current entry0
Meloxicam and rizatriptanSymbravonone listed$122.64 per tablet 20-10 mg tabletYesNo current entry0

Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)

What do pharmacies pay?

Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What next?