FDA data Registry peer set 13 peers

Alternatives to naproxen

13 same-class SPL records vs naproxen - uses, FAERS reaction fields, and OTC/Rx flags from public FDA sources.

Brand: Aleve, Naprosyn

Nonsteroidal Anti-Inflammatory Drug (NSAID) OTC 13 alternatives found

How to read a high-report FAERS peer set

naproxen ranks in the upper FAERS-volume third of the corpus (#97 of 524); 13 same-class peers are listed for field comparison only. Labeled indication field for naproxen: Naproxen is used to relieve pain and inflammation.

Top FAERS reaction fields for naproxen total 60,120 reports across 10 reactions, set beside diclofenac, diflunisal, etodolac. Counts are exposure-weighted submissions, not per-patient risk.

About naproxen

Naproxen is a nonsteroidal anti-inflammatory drug (NSAID). It helps reduce pain, swelling, and stiffness.

Used for: Naproxen is used to relieve pain and inflammation. You can use it for arthritis, including rheumatoid arthritis and osteoarthritis. It also treats ankylosing spondylitis and juvenile idiopathic arthritis. Naproxen can help with tendonitis, bursitis, gout, menstrual cramps, and general pain.

13 Nonsteroidal Anti-Inflammatory Drug (NSAID) peers (wide set)

diclofenac

OTC

Voltaren, Cataflam

This medicine temporarily relieves arthritis pain. It is only for pain in your hands, wrists, elbows, feet, ankles, or knees. It may take up to 7 days to start working. If you still have pain after 7 days, stop using it.

diflunisal

Rx

Dolobid

Diflunisal can help with mild to moderate pain. It can also treat the symptoms of osteoarthritis and rheumatoid arthritis. You should use the lowest dose that works for you, for the shortest time needed.

etodolac

Rx

Lodine

Etodolac treats the symptoms of osteoarthritis and rheumatoid arthritis. It can help with pain and swelling in your joints. Etodolac is also used for short-term relief of acute pain.

ibuprofen

OTC

Advil, Motrin

Ibuprofen can help with minor aches and pains. You can use it for headaches, toothaches, backaches, menstrual cramps, and muscle aches. It can also help with the common cold, minor arthritis pain, and fever.

indomethacin

Rx

Indocin

Indomethacin treats moderate to severe rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It can also help with acute painful shoulder (bursitis or tendinitis) and gouty arthritis. This medicine reduces pain and swelling in your joints.

ketoprofen

Rx

Orudis

Ketoprofen extended-release capsules treat the symptoms of rheumatoid arthritis and osteoarthritis. These conditions cause pain, swelling, and stiffness in the joints. This medicine is not for treating sudden, sharp pain.

ketorolac

Rx

Toradol

Ketorolac is used for short-term relief of moderate to severe pain. It is often used after surgery. You should only use it for up to 5 days.

mefenamic acid

Rx

Ponstel

Mefenamic acid is used to relieve mild to moderate pain in people 14 years and older. It should not be used for more than 7 days. It is also used to treat menstrual cramps.

meloxicam

Rx

Mobic

Meloxicam treats the symptoms of osteoarthritis and rheumatoid arthritis. It can also treat juvenile rheumatoid arthritis in children who weigh at least 132 pounds (60 kg). This medicine helps to relieve pain, swelling, and stiffness in your joints.

nabumetone

Rx

Relafen

Nabumetone is used to relieve the symptoms of osteoarthritis and rheumatoid arthritis. These conditions can cause pain, swelling, and stiffness in your joints. This medicine can help you feel better.

oxaprozin

Rx

Daypro

This medicine can help with the symptoms of osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis. These conditions can cause pain, swelling, and stiffness in your joints. Oxaprozin can help you feel better by reducing these symptoms.

piroxicam

Rx

Feldene

Piroxicam helps to relieve the pain and swelling from osteoarthritis and rheumatoid arthritis. Osteoarthritis is a joint problem that usually affects older people. Rheumatoid arthritis is a disease that causes joint pain, swelling, and stiffness.

sulindac

Rx

Clinoril

Sulindac can help with the pain and swelling from different types of arthritis. This includes osteoarthritis and rheumatoid arthritis. It can also treat ankylosing spondylitis, a painful shoulder, and gout.

Compare naproxen vs diclofenac side-by-side →

naproxen vs diclofenac & diflunisal · FAERS reaction fields

FAERS top-reaction field "Fatigue" shows the widest count spread between naproxen and diclofenac, diflunisal, etodolac in this extract (3,978-report gap on that field). Counts are exposure-weighted submissions, not prevalence rates.

Side Effect naproxen diclofenacdiflunisaletodolac
Pain 8,756 12,281 50 350
Fatigue 7,339 11,317 57 272
Arthralgia 7,243 8,640 43 284
Nausea 7,062 6,715 66 290
Headache 5,716 6,585 45 238
Diarrhoea 5,350 - 43 234
Vomiting 4,746 - 28 150
Dizziness 4,711 - 32 207

"-" means no reports for that reaction. Report counts reflect total FAERS submissions, not prevalence rates.

naproxen FAERS volume vs class peers

FAERS volume band

naproxen is FAERS corpus rank #97 of 524 (high volume tercile). Top-reaction field total: 60,120.

Frequently Asked Questions

Where does naproxen sit in FAERS report volume vs Nonsteroidal Anti-Inflammatory Drug (NSAID) peers?
naproxen ranks #97 of 524 drugs by FAERS top-reaction report volume (high volume tercile). Top-reaction fields total 60,120 submissions in this extract, exposure-weighted counts, not per-patient risk.

Registry note: FAERS counts are voluntary reports and do not establish causation or risk rates. This information is for educational purposes only and is not a substitute for professional medical advice. Do not stop or change your medication without talking to your doctor or pharmacist.

Full naproxen profile →

Field note for naproxen: see also the generic vs brand label guide when reading Aleve SPL strings.