What the FDA labels say about taking them together
Febuxostat and rosuvastatin
Rosuvastatin's FDA label of September 4, 2026 names febuxostat in its drug interactions section; the febuxostat label PlainMeds reads does not name rosuvastatin. The rosuvastatin label: “Mechanism and Clinical Effect (s): Febuxostat increased rosuvastatin exposure more than 1.9-fold.”
Check it at the source: the febuxostat FDA label on DailyMed (effective December 24, 2025, Takeda Pharmaceuticals America, Inc.); the rosuvastatin FDA label on DailyMed (effective September 4, 2026, ScieGen Pharmaceuticals, Inc.).
What does the febuxostat label say about rosuvastatin?
Febuxostat's label (effective December 24, 2025) does not name rosuvastatin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (ULORIC), Takeda Pharmaceuticals America, Inc., effective December 24, 2025 (SPL set 54de10ef-fe5f-4930-b91d-6bbb04c664bd), via openFDA; the full label on DailyMed
What does the rosuvastatin label say about febuxostat?
Rosuvastatin label, drug interactionsMechanism and Clinical Effect (s): Febuxostat increased rosuvastatin exposure more than 1.9-fold.
Source: FDA drug label (Rosuvastatin), ScieGen Pharmaceuticals, Inc., effective September 4, 2026 (SPL set ee4933c5-0d97-494d-ac0f-2083e0100836), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Febuxostat | Rosuvastatin | |
|---|---|---|
| Labeled for | Gout | Heart attack and coronary artery disease, High cholesterol, High triglycerides, Stroke prevention |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.191 per tablet 40 mg tablet | $0.0692 per tablet 40 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once