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What the FDA labels say about taking them together

Haloperidol and propranolol

Propranolol's FDA label of January 15, 2026 names haloperidol in its drug interactions section; the haloperidol labels PlainMeds reads (2) do not name propranolol. The propranolol label: “Neuroleptic Drugs Hypotension and cardiac arrest have been reported with the concomitant use of propranolol and haloperidol.”

Check it at the source: the haloperidol FDA label on DailyMed (effective April 23, 2026, PD-Rx Pharmaceuticals, Inc.); the propranolol FDA label on DailyMed (effective January 15, 2026, Mylan Pharmaceuticals Inc.).

What does the haloperidol label say about propranolol?

Haloperidol's label (effective April 23, 2026) and its 1 other brand-application label do not name propranolol in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Haloperidol), PD-Rx Pharmaceuticals, Inc., effective April 23, 2026 (SPL set 533b0b4c-cbd6-4ec0-a333-8b04b5b43a1d), via openFDA; the full label on DailyMed

What does the propranolol label say about haloperidol?

Propranolol label, drug interactions

Neuroleptic Drugs Hypotension and cardiac arrest have been reported with the concomitant use of propranolol and haloperidol.

Source: FDA drug label (Propranolol Hydrochloride), Mylan Pharmaceuticals Inc., effective January 15, 2026 (SPL set b94dcec7-7633-4a33-9cea-48161adeaf93), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

41Haloperidol generic labelers
42Propranolol generic labelers
HaloperidolPropranolol
Labeled forSchizophreniaHigh blood pressure, Angina, Atrial fibrillation, Migraine
Boxed warningYesNo
Pharmacy cost (NADAC)$15.60 per mL 100 mg/mL vial$0.0493 per tablet 20 mg tablet
Shortage nowA presentation being discontinuedIn shortage

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?