Potassium Chloride and Glycopyrrolate Interaction
Drug interaction information between Potassium Chloride and Glycopyrrolate.
Potassium Chloride and Glycopyrrolate have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Potassium Chloride and Glycopyrrolate. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Glycopyrrolate slows down your digestion, which can cause potassium tablets to sit in your stomach or intestines too long and cause sores.
FDA Label Information
Concomitant administration of glycopyrrolate injection and potassium chloride in a wax matrix may increase the severity of potassium chloride-induced gastrointestinal lesions as a result of a slower gastrointestinal transit time.
Potassium Chloride Also Interacts With
- Amiloride major
- Spironolactone minor
- Eplerenone minor
- Aliskiren minor
- Prenatal Multivitamin minor
Frequently Asked Questions
What SPL severity band is on file for Potassium Chloride + Glycopyrrolate?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Potassium Chloride has 6 labeled pairs on file vs Glycopyrrolate's 2. In the minor band specifically: Potassium Chloride has 5 (also Spironolactone, Eplerenone, Aliskiren, Prenatal Multivitamin); Glycopyrrolate has 2 (also Midazolam).
What mechanism field is on file for Potassium Chloride and Glycopyrrolate?
Glycopyrrolate slows down your digestion, which can cause potassium tablets to sit in your stomach or intestines too long and cause sores.
Potassium Chloride carries more major-labeled pairs than Glycopyrrolate
SPL source-record counts only. This page's band is minor · classes on file: Potassium Chloride (Electrolyte Supplement); Glycopyrrolate (Long-Acting Muscarinic Antagonist (LAMA)).
Potassium Chloride has 1 major-labeled pair vs Glycopyrrolate's 0. This page itself is in the minor band, not the major band.
1 major · 0 moderate · 5 minor · 6 total
- Other minor peers for Potassium Chloride
- Spironolactone
- Eplerenone
- Aliskiren
- Prenatal Multivitamin
0 major · 0 moderate · 2 minor · 2 total
- Other minor peers for Glycopyrrolate
- Midazolam
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.