What the FDA labels say about taking them together
Pitavastatin and rifampin
Pitavastatin's FDA label of March 31, 2026 names rifampin in its drug interactions section; the rifampin label PlainMeds reads does not name pitavastatin. The pitavastatin label: “Rifampin significantly increases peak pitavastatin exposure and increases the risk of myopathy and rhabdomyolysis.”
Check it at the source: the pitavastatin FDA label on DailyMed (effective March 31, 2026, Kowa Pharmaceuticals America, Inc.); the rifampin FDA label on DailyMed (effective February 11, 2026, Lupin Pharmaceuticals, Inc.).
What does the pitavastatin label say about rifampin?
Pitavastatin label, drug interactionsClinical Impact: Rifampin significantly increases peak pitavastatin exposure and increases the risk of myopathy and rhabdomyolysis. Intervention: In patients taking rifampin, do not exceed LIVALO 2 mg once daily [see Dosage and Administration (2.4) ].
Pitavastatin label, warnings and precautionsThere are LIVALO dosage restrictions for patients taking erythromycin or rifampin [see Dosage and Administration (2.4) ].
Source: FDA drug label (Zypitamag, NDA208379), Medicure International Inc, effective December 3, 2025 (SPL set c8c50e03-5cb8-43f4-bdef-8edd12f1945f), via openFDA
Source: FDA drug label (Livalo), Kowa Pharmaceuticals America, Inc., effective March 31, 2026 (SPL set 44dcbf97-99ec-427c-ba50-207e0069d6d2), via openFDA; the full label on DailyMed
What does the rifampin label say about pitavastatin?
Rifampin's label (effective February 11, 2026) does not name pitavastatin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (rifampin), Lupin Pharmaceuticals, Inc., effective February 11, 2026 (SPL set b56004f0-f23d-47f6-80c7-39884fccbccc), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Pitavastatin | Rifampin | |
|---|---|---|
| Labeled for | High cholesterol | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.954 per tablet 2 mg tablet | $0.679 per capsule 300 mg capsule |
| Shortage now | No current entry | In shortage |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once