Pindolol and Hydralazine Interaction

Drug interaction information between Pindolol and Hydralazine.

Pindolol and Hydralazine have a documented minor interaction in FDA labeling.

FDA drug labeling documents a minor-severity interaction between Pindolol and Hydralazine. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.

Drug A

Pindolol

Beta-Blocker with ISA

Drug B

Hydralazine

Vasodilator

How They Interact

These two blood pressure medicines can be used together safely. They do not have any harmful interactions when taken at the same time.

FDA Label Information

Pindolol has been used with a variety of antihypertensive agents, including hydrochlorothiazide, hydralazine, and guanethidine without unexpected adverse interactions.

Hydralazine Also Interacts With

View all Hydralazine interactions →

Frequently Asked Questions

What SPL severity band is on file for Pindolol + Hydralazine?

Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.

Which drug in this pair has the larger labeled-interaction portfolio?

Pindolol has 4 labeled pairs on file vs Hydralazine's 3. In the minor band specifically: Pindolol has 4 (also Hydrochlorothiazide, Epinephrine, Thioridazine); Hydralazine has 3 (also Alosetron, Enalapril).

What mechanism field is on file for Pindolol and Hydralazine?

These two blood pressure medicines can be used together safely. They do not have any harmful interactions when taken at the same time.

Pindolol's labeled portfolio outnumbers Hydralazine

SPL source-record counts only. This page's band is minor · classes on file: Pindolol (Beta-Blocker with ISA); Hydralazine (Vasodilator).

Pindolol

0 major · 0 moderate · 4 minor · 4 total

Hydralazine

0 major · 0 moderate · 3 minor · 3 total

Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.