hydralazine vs pindolol
Side-by-side comparison of hydralazine and pindolol. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
Pindolol has been used with a variety of antihypertensive agents, including hydrochlorothiazide, hydralazine, and guanethidine without unexpected adverse interactions.
Recommendation: You can take these medications together as prescribed. Your doctor will monitor your blood pressure to ensure the treatment is working.
Apresoline
Visken
Hydralazine is a drug that lowers blood pressure by relaxing blood vessels. It can be used alone or with other medications.
Pindolol is a medicine that lowers high blood pressure. It belongs to a class of drugs called beta-blockers.
Hydralazine is used to treat high blood pressure (hypertension). It can be used by itself or with other blood pressure medicines. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.
Pindolol treats high blood pressure. You can take it alone or with other blood pressure medicines. It often works well when combined with a water pill (diuretic).
Hydralazine works by relaxing the muscles in your blood vessels. This allows blood to flow more easily. As a result, your blood pressure goes down.
Pindolol blocks the effects of certain natural chemicals in your body, like adrenaline. This helps to slow down your heart rate and lower your blood pressure. It also has some stimulating activity of its own.
- • Headache
- • Loss of appetite
- • Nausea
- • Vomiting
- • Diarrhea
- • Bizarre or many dreams
- • Dizziness
- • Fatigue
- • Insomnia
- • Nervousness
- Long-term kidney disease 2,819
- Sudden kidney damage 2,616
- Kidney failure 2,097
- Final stage of kidney failure 1,585
- Tiredness 1,541
- Feeling tired 43
- Feeling sick to your stomach 43
- Bladder infection 42
- Feeling lightheaded 41
- The medicine is interacting with another medicine 40
Taking high doses of hydralazine can cause a drug-induced lupus erythematosus (L.E.) cell syndrome. Your doctor will monitor your dose to avoid this.
You should not take pindolol if you have asthma, heart failure, cardiogenic shock, second or third-degree heart block, or a very slow heart rate.
Tell your doctor if you are pregnant or plan to become pregnant. It is not known if hydralazine will harm an unborn baby. Talk to your doctor about the risks and benefits of taking hydralazine during pregnancy or while breastfeeding.
Tell your doctor if you are pregnant or plan to become pregnant. It is not known if pindolol will harm your unborn baby. Talk to your doctor about the risks and benefits of taking pindolol while breastfeeding.
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How to Read This hydralazine vs pindolol Comparison
hydralazine is classified in the Vasodilator drug class, while pindolol sits within the Beta-Blocker with ISA class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, hydralazine has 10,658 submissions while pindolol has 209. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to these two blood pressure medicines can be used together safely. they do not have any harmful interactions when taken at the same time.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between hydralazine and pindolol - always consult your physician or pharmacist first.
Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.