What the FDA labels say about taking them together
Hydrochlorothiazide and pindolol
Pindolol's FDA label of March 17, 2026 names hydrochlorothiazide in its drug interactions section; the hydrochlorothiazide labels PlainMeds reads (3) do not name pindolol.
Check it at the source: the hydrochlorothiazide FDA label on DailyMed (effective June 12, 2026, Leading Pharma, LLC); the pindolol FDA label on DailyMed (effective March 17, 2026, Sun Pharmaceutical Industries, Inc.).
What does the hydrochlorothiazide label say about pindolol?
Hydrochlorothiazide's label (effective June 12, 2026) and its 2 other brand-application labels do not name pindolol in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (HYDROCHLOROTHIAZIDE), Leading Pharma, LLC, effective June 12, 2026 (SPL set 8c868894-667e-4a51-906a-838d63e420ba), via openFDA; the full label on DailyMed
What does the pindolol label say about hydrochlorothiazide?
Pindolol label, drug interactionsPindolol has been used with a variety of antihypertensive agents, including hydrochlorothiazide, hydralazine, and guanethidine without unexpected adverse interactions.
Source: FDA drug label (Pindolol), Sun Pharmaceutical Industries, Inc., effective March 17, 2026 (SPL set b331a73f-bf7b-4442-8901-36d016530279), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Hydrochlorothiazide | Pindolol | |
|---|---|---|
| Labeled for | Heart failure, High blood pressure, Edema (fluid retention) | High blood pressure |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.0115 per tablet 25 mg tablet | $0.854 per tablet 10 mg tablet |
| Shortage now | A presentation being discontinued | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once