Oxcarbazepine and Bictegravir Interaction
Drug interaction information between Oxcarbazepine and Bictegravir.
Oxcarbazepine and Bictegravir have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Oxcarbazepine and Bictegravir. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
This seizure medication lowers the amount of the HIV medicine in your blood, which can make the HIV treatment less effective.
FDA Label Information
oxcarbazepine phenobarbital phenytoin ↓ BIC ↓ TAF Coadministration with alternative anticonvulsants should be considered.
Oxcarbazepine Also Interacts With
- Dolutegravir/Lamivudine moderate
- Tranylcypromine moderate
- Rifampin minor
- Phenytoin minor
- Phenobarbital minor
Bictegravir Also Interacts With
- Rifampin major
- Dofetilide major
- Metformin moderate
- Sertraline minor
- Estradiol minor
Frequently Asked Questions
What SPL severity band is on file for Oxcarbazepine + Bictegravir/Emtricitabine/Tenofovir?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Bictegravir has 19 labeled pairs on file vs Oxcarbazepine's 18. In the minor band specifically: Oxcarbazepine has 16 (also Rifampin, Phenytoin, Phenobarbital, Carbamazepine); Bictegravir has 16 (also Sertraline, Estradiol, Valacyclovir, Acyclovir).
What mechanism field is on file for Oxcarbazepine and Bictegravir/Emtricitabine/Tenofovir?
This seizure medication lowers the amount of the HIV medicine in your blood, which can make the HIV treatment less effective.
Bictegravir carries more major-labeled pairs than Oxcarbazepine
SPL source-record counts only. This page's band is minor · classes on file: Oxcarbazepine (Anticonvulsant); Bictegravir (Integrase Inhibitor / NRTI Combination).
Bictegravir has 2 major-labeled pairs vs Oxcarbazepine's 0. This page itself is in the minor band, not the major band.
0 major · 2 moderate · 16 minor · 18 total
- Other minor peers for Oxcarbazepine
- Rifampin
- Phenytoin
- Phenobarbital
- Carbamazepine
2 major · 1 moderate · 16 minor · 19 total
- Other minor peers for Bictegravir
- Sertraline
- Estradiol
- Valacyclovir
- Acyclovir
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.