Methyldopa and Colestipol Interaction
Drug interaction information between Methyldopa and Colestipol.
Methyldopa and Colestipol have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Methyldopa and Colestipol. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
This drug does not seem to change how much methyldopa gets into your blood when they are taken together.
FDA Label Information
No depressant effect on blood levels in humans was noted when colestipol hydrochloride was administered with any of the following drugs: aspirin, clindamycin, clofibrate, methyldopa, nicotinic acid (niacin), tolbutamide, phenytoin or warfarin.
Methyldopa Also Interacts With
- Ferrous Sulfate moderate
- Carbidopa/Levodopa moderate
- Tranylcypromine moderate
- Lithium minor
- Enalapril minor
Colestipol Also Interacts With
- Olmesartan moderate
- Furosemide minor
- Aspirin minor
- Propranolol minor
- Warfarin minor
Frequently Asked Questions
What SPL severity band is on file for Methyldopa + Colestipol?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Colestipol has 24 labeled pairs on file vs Methyldopa's 7. In the minor band specifically: Methyldopa has 4 (also Lithium, Enalapril, Vasopressin); Colestipol has 23 (also Furosemide, Aspirin, Propranolol, Warfarin).
What mechanism field is on file for Methyldopa and Colestipol?
This drug does not seem to change how much methyldopa gets into your blood when they are taken together.
Colestipol's labeled portfolio outnumbers Methyldopa
SPL source-record counts only. This page's band is minor · classes on file: Methyldopa (Central Alpha-2 Agonist); Colestipol (Bile Acid Sequestrant).
0 major · 3 moderate · 4 minor · 7 total
- Other minor peers for Methyldopa
- Lithium
- Enalapril
- Vasopressin
0 major · 1 moderate · 23 minor · 24 total
- Other minor peers for Colestipol
- Furosemide
- Aspirin
- Propranolol
- Warfarin
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.