Doxazosin and Propranolol Interaction
Drug interaction information between Doxazosin and Propranolol.
Doxazosin and Propranolol have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Doxazosin and Propranolol. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Both drugs lower blood pressure, which can cause a sudden drop in pressure when you stand up. This can make you feel dizzy or faint.
FDA Label Information
Postural hypotension has been reported in patients taking both beta-blockers and terazosin or doxazosin.
Propranolol Also Interacts With
- Clonidine minor
- Diltiazem minor
- Warfarin minor
- Verapamil minor
- Haloperidol minor
Frequently Asked Questions
What SPL severity band is on file for Doxazosin + Propranolol?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Propranolol has 44 labeled pairs on file vs Doxazosin's 2. In the minor band specifically: Doxazosin has 2 (also Tadalafil); Propranolol has 44 (also Clonidine, Diltiazem, Warfarin, Verapamil).
What mechanism field is on file for Doxazosin and Propranolol?
Both drugs lower blood pressure, which can cause a sudden drop in pressure when you stand up. This can make you feel dizzy or faint.
Propranolol's labeled portfolio outnumbers Doxazosin
SPL source-record counts only. This page's band is minor · classes on file: Doxazosin (Alpha-1 Adrenergic Blocker); Propranolol (Non-Selective Beta-Blocker).
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.