Bupropion · more major-labeled pairs than Dopamine
SPL labels Dopamine + Bupropion as minor; Dopamine 23 / Bupropion 32 in that band.
Mechanism on file: Both drugs increase the activity of dopamine in the brain, and taking them together can cause these effects to reach toxic levels.
FDA SPL severity: Minor
Dopamine + Bupropion · SPL mechanism field
Both drugs increase the activity of dopamine in the brain, and taking them together can cause these effects to reach toxic levels.
Minor band excerpt · Dopamine with Bupropion
( 5.3 , 7.3 ) Dopaminergic Drugs (levodopa and amantadine): CNS toxicity can occur when used concomitantly with bupropion hydrochloride extended-release tablets (XL). 7.4 Dopaminergic Drugs (Levodopa and Amantadine) Bupropion, levodopa, and amantadine have dopamine agonist effects. It is presumed that the toxicity results from cumulative dopamine agonist effects.
Dopamine · 23 minor + 28 total pairs
- Amitriptyline minor
- Atomoxetine minor
- Bromocriptine minor
- Desipramine minor
Bupropion · 1 major-labeled pairs (vs Dopamine's 0)
- Brexpiprazole minor
- Carbamazepine minor
- Clopidogrel minor
- Clozapine minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.