What the FDA labels say about taking them together
Amitriptyline and dopamine
Dopamine's FDA label of May 12, 2026 names amitriptyline in its drug interactions section; the amitriptyline label PlainMeds reads does not name dopamine.
Check it at the source: the amitriptyline FDA label on DailyMed (effective September 8, 2026, Sun Pharmaceutical Industries, Inc.); the dopamine FDA label on DailyMed (effective May 12, 2026, Hospira, Inc.).
What does the amitriptyline label say about dopamine?
Amitriptyline's label (effective September 8, 2026) does not name dopamine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Amitriptyline Hydrochloride), Sun Pharmaceutical Industries, Inc., effective September 8, 2026 (SPL set 4e520c63-1cf6-40f6-a51c-3f9b0e181342), via openFDA; the full label on DailyMed
What does the dopamine label say about amitriptyline?
Dopamine label, drug interactionsTricyclic Antidepressants Clinical Impact: Concomitant use may potentiate the cardiovascular effects of dopamine (e.g., hypertension). Intervention: Monitor blood pressure. Examples: amitriptyline, desipramine, doxepin, imipramine, nortriptyline.
Source: FDA drug label (Dopamine Hydrochloride in Dextrose), Hospira, Inc., effective May 12, 2026 (SPL set 08f23f6e-150d-45ea-098e-f2edf64c21a1), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Amitriptyline | Dopamine | |
|---|---|---|
| Labeled for | Depression | n/a |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.03 per tablet 10 mg tablet | n/a |
| Shortage now | No current entry | In shortage |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once