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What the FDA labels say about taking them together

Desipramine and dopamine

Dopamine's FDA label of May 12, 2026 names desipramine in its drug interactions section; the desipramine labels PlainMeds reads (2) do not name dopamine.

Check it at the source: the desipramine FDA label on DailyMed (effective July 9, 2025, Alembic Pharmaceuticals Inc.); the dopamine FDA label on DailyMed (effective May 12, 2026, Hospira, Inc.).

What does the desipramine label say about dopamine?

Desipramine's label (effective July 9, 2025) and its 1 other brand-application label do not name dopamine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (DESIPRAMINE HYDROCHLORIDE), Alembic Pharmaceuticals Inc., effective July 9, 2025 (SPL set cad14805-64d8-4257-b5f1-d56e0063f0e2), via openFDA; the full label on DailyMed

What does the dopamine label say about desipramine?

Dopamine label, drug interactions

Tricyclic Antidepressants Clinical Impact: Concomitant use may potentiate the cardiovascular effects of dopamine (e.g., hypertension). Intervention: Monitor blood pressure. Examples: amitriptyline, desipramine, doxepin, imipramine, nortriptyline.

Source: FDA drug label (Dopamine Hydrochloride in Dextrose), Hospira, Inc., effective May 12, 2026 (SPL set 08f23f6e-150d-45ea-098e-f2edf64c21a1), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

9Desipramine generic labelers
4Dopamine generic labelers
DesipramineDopamine
Labeled forDepressionn/a
Boxed warningYesNo
Pharmacy cost (NADAC)$0.276 per tablet 75 mg tabletn/a
Shortage nowNo current entryIn shortage

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?