HIGH-VOLUME · SEX-BALANCED
hydroxyzine Side Effects
hydroxyzine (also sold as Vistaril, Atarax) is HIGH-VOLUME in this FAERS book #152 of 524 by FAERS report count. Signature opener: SEX-BALANCED - 66% of sex-coded reports are female (26,625 F / 13,607 M).
Data updated 2026-05-15
- 44,206
- FAERS reports
FAERS voluntary reports, 2003 to 2025. High volume tracks exposure and reporting culture; see methodology for de-dup rules.
hydroxyzine reporting skew - 66% of sex-coded reports are female (26,625 F / 13,607 M). Volume band HIGH-VOLUME #152 of 524 by FAERS report count; caseload CASELOAD.
High-report extract for hydroxyzine (Vistaril): 44,206 FAERS rows (2003-2025). Top named reactions: PRURITUS, NAUSEA, FATIGUE. Outcome stamps DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED. FAERS is voluntary signal detection, not incidence.
Counts from the openFDA FAERS extract (2003–2025). Stamps CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
PRURITUS leads 2,965 of 44,206 reports
Who reports · age peak 45-64 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 45-64 (11,383 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (6,351 reports, 14.4%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| COMPLETED SUICIDE | 2,057 |
| TOXICITY TO VARIOUS AGENTS | 1,629 |
| DEATH | 1,208 |
| DRUG ABUSE | 650 |
| CARDIO-RESPIRATORY ARREST | 552 |
| CARDIAC ARREST | 435 |
| RESPIRATORY ARREST | 266 |
| POISONING | 212 |
| OVERDOSE | 210 |
| SUSPECTED SUICIDE | 195 |
| HYPOTENSION | 180 |
| RENAL FAILURE | 146 |
| PNEUMONIA | 144 |
| DYSPNOEA | 137 |
| ACUTE KIDNEY INJURY | 136 |
| DRUG INTERACTION | 136 |
| SEPSIS | 126 |
| VOMITING | 116 |
| PYREXIA | 113 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (13,813, 31.2% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| NAUSEA | 974 |
| DYSPNOEA | 915 |
| TOXICITY TO VARIOUS AGENTS | 899 |
| VOMITING | 802 |
| FALL | 777 |
| FATIGUE | 773 |
| PAIN | 765 |
| PNEUMONIA | 749 |
| HYPOTENSION | 688 |
| ANXIETY | 682 |
| DIARRHOEA | 678 |
| HEADACHE | 658 |
| PYREXIA | 628 |
| PRURITUS | 625 |
| DIZZINESS | 615 |
| ACUTE KIDNEY INJURY | 540 |
| INTENTIONAL OVERDOSE | 532 |
| ASTHENIA | 528 |
How to read hydroxyzine FAERS figures (CASELOAD · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 44,206 voluntary reports linked to hydroxyzine (Vistaril, Atarax), 2003-2025. Death is listed on 6,351 (14.4%). Hospitalization appears on 13,813 (31.2%). Top co-reported indication: Product Used For Unknown Indication.
CASELOAD books overweight common drugs and loud reporting cultures; SEX-BALANCED is the page opener, not a per-patient risk.
Read with hydroxyzine
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 43,650 FAERS cases (Δ 556 lighter vs hydroxyzine); DEATH-MARKED · HOSP-LIGHT · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 43,004 FAERS cases (Δ 1,202 lighter vs hydroxyzine); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 45,410 FAERS cases (Δ 1,204 heavier vs hydroxyzine); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 42,665 FAERS cases (Δ 1,541 lighter vs hydroxyzine); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 47.7 pp vs hydroxyzine's DEATH-HEAVY): CASELOAD · HOSP-MID.
hydroxyzine stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload CASELOAD and the label guide.