HIGH-VOLUME · HOSP-HEAVY
metronidazole topical Side Effects
metronidazole topical (also sold as MetroGel) is HIGH-VOLUME in this FAERS book #150 of 524 by FAERS report count. Signature opener: HOSP-HEAVY - 41.1% mention hospitalization (18,836 reports).
Data updated 2026-05-15
- 45,816
- FAERS reports
FAERS voluntary reports, 1999 to 2025. High volume tracks exposure and reporting culture; see methodology for de-dup rules.
metronidazole topical: 41.1% mention hospitalization (18,836 reports). Death stamp DEATH-HEAVY; volume band HIGH-VOLUME #150 of 524 by FAERS report count.
High-report extract for metronidazole topical (MetroGel): 45,816 FAERS rows (1999-2025). Top named reactions: NAUSEA, DIARRHOEA, VOMITING. Outcome stamps DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED. FAERS is voluntary signal detection, not incidence.
Counts from the openFDA FAERS extract (1999–2025). Stamps CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
NAUSEA leads 3,318 of 45,816 reports
Who reports · age peak 45-64 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 45-64 (10,392 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (5,167 reports, 11.3%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 780 |
| SEPSIS | 654 |
| MULTIPLE ORGAN DYSFUNCTION SYNDROME | 618 |
| SEPTIC SHOCK | 430 |
| GENERAL PHYSICAL HEALTH DETERIORATION | 416 |
| VOMITING | 411 |
| ABDOMINAL PAIN | 407 |
| NAUSEA | 397 |
| CONDITION AGGRAVATED | 390 |
| PNEUMONIA | 341 |
| PYREXIA | 340 |
| ASCITES | 336 |
| ABDOMINAL DISTENSION | 324 |
| RENAL FAILURE | 317 |
| ANAEMIA | 312 |
| DYSPNOEA | 298 |
| CONSTIPATION | 293 |
| HYPONATRAEMIA | 291 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (18,836, 41.1% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| NAUSEA | 1,450 |
| PYREXIA | 1,378 |
| DIARRHOEA | 1,367 |
| ABDOMINAL PAIN | 1,230 |
| VOMITING | 1,197 |
| PAIN | 1,107 |
| ANAEMIA | 905 |
| ACUTE KIDNEY INJURY | 884 |
| DYSPNOEA | 845 |
| HEADACHE | 781 |
| MALAISE | 780 |
| CONDITION AGGRAVATED | 778 |
| WEIGHT DECREASED | 742 |
| FATIGUE | 703 |
| SEPSIS | 703 |
| ASTHENIA | 700 |
| PNEUMONIA | 685 |
| CONSTIPATION | 623 |
How to read metronidazole topical FAERS figures (CASELOAD · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 45,816 voluntary reports linked to metronidazole topical (MetroGel), 1999-2025. Death is listed on 5,167 (11.3%). Hospitalization appears on 18,836 (41.1%). Top co-reported indication: Product Used For Unknown Indication.
CASELOAD books overweight common drugs and loud reporting cultures; HOSP-HEAVY is the page opener, not a per-patient risk.
Read with metronidazole topical
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 45,410 FAERS cases (Δ 406 lighter vs metronidazole topical); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 46,939 FAERS cases (Δ 1,123 heavier vs metronidazole topical); DEATH-RARE · HOSP-LIGHT · FEMALE-LED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 47,215 FAERS cases (Δ 1,399 heavier vs metronidazole topical); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 44,206 FAERS cases (Δ 1,610 lighter vs metronidazole topical); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 50.8 pp vs metronidazole topical's DEATH-HEAVY): CASELOAD · HOSP-MID.
metronidazole topical stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload CASELOAD and the label guide.