HIGH-VOLUME · HOSP-HEAVY
loperamide Side Effects
loperamide (also sold as Imodium) is HIGH-VOLUME in this FAERS book #155 of 524 by FAERS report count. Signature opener: HOSP-HEAVY - 36.3% mention hospitalization (15,486 reports).
Data updated 2026-05-15
- 42,665
- FAERS reports
FAERS voluntary reports, 1999 to 2025. High volume tracks exposure and reporting culture; see methodology for de-dup rules.
loperamide: 36.3% mention hospitalization (15,486 reports). Death stamp DEATH-HEAVY; volume band HIGH-VOLUME #155 of 524 by FAERS report count.
High-report extract for loperamide (Imodium): 42,665 FAERS rows (1999-2025). Top named reactions: DIARRHOEA, NAUSEA, FATIGUE. Outcome stamps DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED. FAERS is voluntary signal detection, not incidence.
Counts from the openFDA FAERS extract (1999–2025). Stamps CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
DIARRHOEA leads 8,463 of 42,665 reports
Who reports · age peak 45-64 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 45-64 (8,862 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (3,775 reports, 8.8%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 1,282 |
| DIARRHOEA | 588 |
| NAUSEA | 301 |
| PNEUMONIA | 291 |
| FATIGUE | 270 |
| DYSPNOEA | 226 |
| VOMITING | 224 |
| ASTHENIA | 214 |
| SEPSIS | 202 |
| DECREASED APPETITE | 200 |
| TOXICITY TO VARIOUS AGENTS | 200 |
| MALIGNANT NEOPLASM PROGRESSION | 173 |
| ANAEMIA | 172 |
| DISEASE PROGRESSION | 167 |
| ABDOMINAL PAIN | 165 |
| DEHYDRATION | 165 |
| PYREXIA | 157 |
| CARDIAC ARREST | 156 |
| HYPOTENSION | 155 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (15,486, 36.3% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| DIARRHOEA | 3,268 |
| NAUSEA | 1,982 |
| VOMITING | 1,533 |
| FATIGUE | 1,413 |
| PNEUMONIA | 1,314 |
| DEHYDRATION | 1,200 |
| PYREXIA | 1,064 |
| DYSPNOEA | 1,063 |
| WEIGHT DECREASED | 996 |
| ABDOMINAL PAIN | 986 |
| ASTHENIA | 915 |
| DECREASED APPETITE | 815 |
| ANAEMIA | 772 |
| PAIN | 757 |
| HEADACHE | 728 |
| CONSTIPATION | 689 |
| MALAISE | 673 |
| DIZZINESS | 654 |
How to read loperamide FAERS figures (CASELOAD · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 42,665 voluntary reports linked to loperamide (Imodium), 1999-2025. Death is listed on 3,775 (8.8%). Hospitalization appears on 15,486 (36.3%). Top co-reported indication: Product Used For Unknown Indication.
CASELOAD books overweight common drugs and loud reporting cultures; HOSP-HEAVY is the page opener, not a per-patient risk.
Read with loperamide
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 42,504 FAERS cases (Δ 161 lighter vs loperamide); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 43,004 FAERS cases (Δ 339 heavier vs loperamide); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 41,778 FAERS cases (Δ 887 lighter vs loperamide); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 43,650 FAERS cases (Δ 985 heavier vs loperamide); DEATH-MARKED · HOSP-LIGHT · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 53.3 pp vs loperamide's DEATH-HEAVY): CASELOAD · HOSP-MID.
loperamide stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload CASELOAD and the label guide.