Medicines labeled for the same conditions

Alternatives to trifluoperazine

18 other medicines are given the same way (oral) and in the same FDA class as trifluoperazine or labeled mainly for the same use (schizophrenia); 4 are in its class, phenothiazines: chlorpromazine, perphenazine, prochlorperazine and amitriptyline and perphenazine; the others include 8 atypical antipsychotics, 3 typical antipsychotics and 1 cholinergic muscarinic agonist (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $0.161 per perphenazine 4 mg tablet (what pharmacies paid in the NADAC survey; strengths differ).

Which medicines are labeled for the same conditions as trifluoperazine?

Schizophrenia lists all 24 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.

Medicine and FDA class	Shared indication	Generic labelers (oral)	Pharmacy cost	Boxed warning	Shortage
Trifluoperazinephenothiazine	this medicine	6 labelers	$0.579 per tablet 2 mg tablet	Yes	No current entry
Chlorpromazinephenothiazine · same class	Schizophrenia	22 labelers	$0.552 per tablet 100 mg tablet	Yes	No current entry
Perphenazinephenothiazine · same class	Schizophrenia	16 labelers	$0.161 per tablet 4 mg tablet	Yes	No current entry
Prochlorperazinephenothiazine · same class	Anxiety, Schizophrenia	29 labelers	$0.162 per tablet 10 mg tablet	Yes	No current entry
Amitriptyline and perphenazinetricyclic antidepressant · same class	Anxiety	1 labeler	n/a	Yes	No current entry
Quetiapineatypical antipsychotic	Schizophrenia	50 labelers	$0.127 per tablet 300 mg tablet	Yes	No current entry
Olanzapineatypical antipsychotic	Schizophrenia	33 labelers	$0.147 per tablet 20 mg tablet	Yes	No current entry
Haloperidoltypical antipsychotic	Schizophrenia	28 labelers	$0.181 per tablet 5 mg tablet	Yes	A presentation being discontinued
Lurasidoneatypical antipsychotic	Schizophrenia	29 labelers	$0.142 per tablet 20 mg tablet	Yes	No current entry
Paliperidoneatypical antipsychotic	Schizophrenia	18 labelers	$0.972 per tablet 3 mg tablet	Yes	No current entry
Clozapineatypical antipsychotic	Schizophrenia	11 labelers	$0.610 per tablet 100 mg tablet	Yes	No current entry
Iloperidoneatypical antipsychotic	Schizophrenia	1 labeler	$60.01 per tablet 12 mg tablet	Yes	No current entry
Loxapine	Schizophrenia	7 labelers	$0.468 per capsule 10 mg capsule	Yes	No current entry
Milsaperidone	Schizophrenia	none listed	n/a	Yes	No current entry
Thiothixenetypical antipsychotic	Schizophrenia	4 labelers	$1.72 per capsule 10 mg capsule	Yes	No current entry
Cariprazineatypical antipsychotic	Schizophrenia	none listed	$50.84 per capsule 1.5 mg capsule	Yes	No current entry
Lumateperoneatypical antipsychotic	Schizophrenia	none listed	$57.24 per capsule 10.5 mg capsule	Yes	No current entry
Molindonetypical antipsychotic	Schizophrenia	1 labeler	n/a	Yes	No current entry
Trospium and xanomelinecholinergic muscarinic agonist	Schizophrenia	none listed	$30.13 per capsule 100 mg-20 mg capsule	No	No current entry

Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)

What do pharmacies pay for each?

The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What next?

Trifluoperazine: the full record: label, generics, price, shortages, recalls