Alternatives to perphenazine
3 same-class SPL records vs perphenazine - uses, FAERS reaction fields, and OTC/Rx flags from public FDA sources.
Brand: Trilafon
About perphenazine
Perphenazine is a medicine used to treat schizophrenia and control severe nausea and vomiting. It belongs to a class of drugs called typical antipsychotics.
Used for: Perphenazine is used to treat schizophrenia in adults. Schizophrenia is a mental illness that can affect how you think, feel, and behave. This medicine can also help control severe nausea and vomiting in adults.
3 Typical Antipsychotic (Phenothiazine) peers (wide set)
chlorpromazine
RxThorazine
Chlorpromazine can treat psychotic disorders like schizophrenia. It can also control nausea and vomiting. Additionally, it can help with restlessness before surgery, acute intermittent porphyria, tetanus, manic episodes of bipolar disorder, and intractable hiccups. In children, it can treat severe behavioral problems and hyperactivity.
fluphenazine
RxProlixin
Fluphenazine is used to manage the symptoms of psychotic disorders. These disorders can cause problems with thinking, feeling, and behavior. This medicine can help reduce hallucinations and other symptoms of psychosis.
thioridazine
RxMellaril
Thioridazine is used to manage schizophrenia in adults and children. You should only use this medicine if other antipsychotic medicines have not worked for you. This is because thioridazine can cause serious heart problems.
perphenazine vs chlorpromazine & fluphenazine · FAERS reaction fields
FAERS top-reaction field "Weight Increased" shows the widest count spread between perphenazine and chlorpromazine, fluphenazine, thioridazine in this extract (214-report gap on that field). Counts are exposure-weighted submissions, not prevalence rates.
| Side Effect | perphenazine | chlorpromazine | fluphenazine | thioridazine |
|---|---|---|---|---|
| Toxicity To Various Agents | 274 | 425 | - | 6 |
| Weight Increased | 222 | - | - | 8 |
| Akathisia | 184 | - | 8 | 5 |
| Suicide Attempt | 180 | 214 | 12 | - |
| Obsessive-Compulsive Disorder | 163 | - | - | - |
| Increased Appetite | 155 | - | - | - |
| Euphoric Mood | 153 | - | - | - |
| Antipsychotic Drug Level Below Therapeutic | 149 | - | - | - |
"-" means no reports for that reaction. Report counts reflect total FAERS submissions, not prevalence rates.
perphenazine peer mix vs class inventory
Peer mix
0 OTC and 3 Rx SPL records in this peer set (3 total). Class inventory for Typical Antipsychotic (Phenothiazine): 4 drugs.
Frequently Asked Questions
What same-class SPL records sit beside perphenazine? ▼
Reading a wide Typical Antipsychotic (Phenothiazine) peer set (3 records)
perphenazine (Trilafon) sits in a wide Typical Antipsychotic (Phenothiazine) peer set (3 of 3 class peers shown). Labeled indication field for perphenazine: Perphenazine is used to treat schizophrenia in adults.
Top FAERS reaction fields for perphenazine total 1,770 reports across 10 reactions, set beside chlorpromazine, fluphenazine, thioridazine. Counts are exposure-weighted submissions, not per-patient risk.
Registry note: Therapeutic-class peer lists are registry indexes, not prescribing advice. This information is for educational purposes only and is not a substitute for professional medical advice. Do not stop or change your medication without talking to your doctor or pharmacist.
Field note for perphenazine: see also the generic vs brand label guide when reading Trilafon SPL strings.
Read our methodology - how this data is sourced, computed, and verified.