Medicines labeled for the same conditions
Alternatives to nitrofurantoin
18 other medicines are given the same way (oral) and in the same FDA class as nitrofurantoin or labeled mainly for the same use (urinary tract infections); the others include 4 cephalosporin antibacterials, 2 tetracycline-class drugs and 1 beta lactamase inhibitor (FDA labels read October 8, 2026).
Which medicines are labeled for the same conditions as nitrofurantoin?
Urinary tract infections lists all 39 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.
| Medicine and FDA class | Shared indication | Generic labelers (oral) | Pharmacy cost | Boxed warning | Shortage |
|---|---|---|---|---|---|
| Nitrofurantoinnitrofuran antibacterial | this medicine | 47 labelers | $0.165 per capsule 50 mg capsule | No | A presentation being discontinued |
| Doxycyclinetetracycline-class drug | Bacterial infections, Urinary tract infections | 71 labelers | $0.118 per tablet 100 mg tablet | No | A presentation being discontinued |
| Amoxicillin and clavulanatebeta lactamase inhibitor | Bacterial infections, Urinary tract infections | 31 labelers | $0.0693 per mL 600-42.9 mg/5 mL sus | No | No current entry |
| Cephalexincephalosporin antibacterial | Bacterial infections, Urinary tract infections | 36 labelers | $0.120 per capsule 500 mg capsule | No | No current entry |
| Minocyclinetetracycline-class drug | Urinary tract infections | 21 labelers | $0.343 per capsule 100 mg capsule | No | No current entry |
| Sulfamethoxazole and trimethoprimsulfonamide antimicrobial | Bacterial infections, Urinary tract infections | 42 labelers | $0.0448 per tablet Sulfamethoxazole-tmp ds tablet | No | No current entry |
| Levofloxacinfluoroquinolone antibacterial | Bacterial infections, Urinary tract infections | 35 labelers | $0.259 per tablet 750 mg tablet | Yes | No current entry |
| Cefuroximecephalosporin antibacterial | Bacterial infections, Urinary tract infections | 17 labelers | $0.280 per tablet 250 mg tablet | No | No current entry |
| Cefadroxilcephalosporin antibacterial | Bacterial infections, Urinary tract infections | 19 labelers | $0.269 per capsule 500 mg capsule | No | No current entry |
| Cefiximecephalosporin antibacterial | Bacterial infections, Urinary tract infections | 6 labelers | $10.03 per capsule 400 mg capsule | No | No current entry |
| Methenamine | Urinary tract infections | 10 labelers | $0.313 per tablet 1 g tablet | No | No current entry |
| Fosfomycin | Urinary tract infections | 10 labelers | $26.22 per unit 3 g sachet | No | No current entry |
| Demeclocyclinetetracycline-class antimicrobial | Bacterial infections, Urinary tract infections | 5 labelers | $2.27 per tablet 150 mg tablet | No | No current entry |
| Trimethoprimdihydrofolate reductase inhibitor antibacterial | Bacterial infections, Urinary tract infections | 4 labelers | $1.31 per tablet 100 mg tablet | No | No current entry |
| Sulfadiazinesulfonamide antibacterial | Urinary tract infections | 2 labelers | $15.06 per tablet 500 mg tablet | No | No current entry |
| Cycloserine | Bacterial infections, Urinary tract infections | 1 labeler | n/a | No | No current entry |
| Gepotidacintriazaacenaphthylene bacterial type ii topoisomerase inhibitor | Urinary tract infections | none listed | $91.40 per tablet 750 mg tablet | No | No current entry |
| Pivmecillinam | Urinary tract infections | none listed | n/a | No | No current entry |
| Probenecid and sulopenem etzadroxil | Urinary tract infections | none listed | n/a | No | No current entry |
Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)
What do pharmacies pay for each?
The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
What next?
- Nitrofurantoin: the full record
- label, generics, price, shortages, recalls
- Nitrofurantoin vs doxycycline
- two records side by side
- Nitrofurantoin vs cephalexin
- two records side by side
- Levofloxacin vs nitrofurantoin
- two records side by side
- Cefuroxime vs nitrofurantoin
- two records side by side