Alternatives to esomeprazole
5 same-class SPL records vs esomeprazole - uses, FAERS reaction fields, and OTC/Rx flags from public FDA sources.
Brand: Nexium
How to read a high-report FAERS peer set
esomeprazole ranks in the upper FAERS-volume third of the corpus (#124 of 524); 5 same-class peers are listed for field comparison only. Labeled indication field for esomeprazole: This medicine treats frequent heartburn.
Top FAERS reaction fields for esomeprazole total 35,792 reports across 10 reactions, set beside dexlansoprazole, lansoprazole, omeprazole. Counts are exposure-weighted submissions, not per-patient risk.
About esomeprazole
Esomeprazole (Nexium) is a drug that reduces stomach acid. It belongs to a class of drugs called proton pump inhibitors (PPIs).
Used for: This medicine treats frequent heartburn. Frequent heartburn means you have heartburn 2 or more days a week. This medicine is not for immediate relief of heartburn. It may take 1 to 4 days to work fully.
5 Proton Pump Inhibitor (PPI) peers (wide set)
dexlansoprazole
RxDexilant
This medicine can help heal damage to your esophagus (the tube connecting your mouth to your stomach). It can also help with heartburn caused by acid reflux. Dexlansoprazole can also treat heartburn from GERD, a condition where stomach acid flows back into your esophagus.
lansoprazole
OTCPrevacid
Lansoprazole can treat several conditions caused by too much stomach acid. It can heal duodenal and gastric ulcers. It also treats heartburn (GERD) and a damaged esophagus (erosive esophagitis).
omeprazole
OTCPrilosec
This medicine treats frequent heartburn, which is heartburn that occurs 2 or more days a week. It is not meant to give you immediate relief from heartburn. It may take 1 to 4 days for the medicine to fully work.
pantoprazole
RxProtonix
This medicine treats gastroesophageal reflux disease (GERD) and erosive esophagitis (EE) in adults, for up to 10 days. GERD is when stomach acid flows back into your esophagus, causing heartburn. It also treats conditions where your stomach makes too much acid, like Zollinger-Ellison (ZE) Syndrome.
rabeprazole
RxAciphex
This medicine can treat several conditions caused by too much stomach acid. It can heal damage to your esophagus from acid reflux (GERD). It also treats heartburn, stomach ulcers, and conditions like Zollinger-Ellison syndrome where the body makes too much acid. Rabeprazole can also be used with antibiotics to get rid of a bacteria called H. pylori that can cause ulcers.
esomeprazole vs dexlansoprazole & lansoprazole · FAERS reaction fields
FAERS top-reaction field "Chronic Kidney Disease" shows the widest count spread between esomeprazole and dexlansoprazole, lansoprazole, omeprazole in this extract (27,755-report gap on that field). Counts are exposure-weighted submissions, not prevalence rates.
| Side Effect | esomeprazole | dexlansoprazole | lansoprazole | omeprazole |
|---|---|---|---|---|
| Chronic Kidney Disease | 5,020 | 16,100 | 32,775 | 13,547 |
| Acute Kidney Injury | 4,563 | 7,791 | 18,670 | 11,753 |
| Nausea | 4,004 | 2,138 | 8,964 | 19,842 |
| Diarrhoea | 3,869 | 1,947 | 8,752 | 19,627 |
| Fatigue | 3,528 | 2,337 | 7,633 | 19,901 |
| Headache | 3,509 | 1,902 | 6,742 | 14,629 |
| Dyspnoea | 3,268 | 1,542 | 7,945 | 16,336 |
| Pain | 2,752 | 1,902 | 6,733 | 13,759 |
"-" means no reports for that reaction. Report counts reflect total FAERS submissions, not prevalence rates.
esomeprazole FAERS volume vs class peers
FAERS volume band
esomeprazole is FAERS corpus rank #124 of 524 (high volume tercile). Top-reaction field total: 35,792.
Frequently Asked Questions
Where does esomeprazole sit in FAERS report volume vs Proton Pump Inhibitor (PPI) peers? ▼
Registry note: FAERS counts are voluntary reports and do not establish causation or risk rates. This information is for educational purposes only and is not a substitute for professional medical advice. Do not stop or change your medication without talking to your doctor or pharmacist.
Field note for esomeprazole: see also the generic vs brand label guide when reading Nexium SPL strings.
Read our methodology - how this data is sourced, computed, and verified.