Medicines labeled for the same conditions

Alternatives to clozapine

20 other medicines are given the same way (oral) and in the same FDA class as clozapine or labeled mainly for the same use (schizophrenia); 11 are in its class, atypical antipsychotics: quetiapine, aripiprazole, olanzapine, risperidone and 7 more; the others include 3 typical antipsychotics, 3 phenothiazines and 1 cholinergic muscarinic agonist (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $0.0368 per risperidone 0.25 mg tablet (what pharmacies paid in the NADAC survey; strengths differ).

Which medicines are labeled for the same conditions as clozapine?

Schizophrenia lists all 24 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.

Medicine and FDA class	Shared indication	Generic labelers (oral)	Pharmacy cost	Boxed warning	Shortage
Clozapineatypical antipsychotic	this medicine	11 labelers	$0.610 per tablet 100 mg tablet	Yes	No current entry
Quetiapineatypical antipsychotic · same class	Schizophrenia	50 labelers	$0.127 per tablet 300 mg tablet	Yes	No current entry
Aripiprazoleatypical antipsychotic · same class	Schizophrenia	47 labelers	$0.110 per tablet 5 mg tablet	Yes	No current entry
Olanzapineatypical antipsychotic · same class	Schizophrenia	33 labelers	$0.147 per tablet 20 mg tablet	Yes	No current entry
Risperidoneatypical antipsychotic · same class	Schizophrenia	35 labelers	$0.0368 per tablet 0.25 mg tablet	Yes	No current entry
Lurasidoneatypical antipsychotic · same class	Schizophrenia	29 labelers	$0.142 per tablet 20 mg tablet	Yes	No current entry
Ziprasidoneatypical antipsychotic · same class	Schizophrenia	16 labelers	$0.269 per capsule 20 mg capsule	Yes	No current entry
Paliperidoneatypical antipsychotic · same class	Schizophrenia	18 labelers	$0.972 per tablet 3 mg tablet	Yes	No current entry
Iloperidoneatypical antipsychotic · same class	Schizophrenia	1 labeler	$60.01 per tablet 12 mg tablet	Yes	No current entry
Brexpiprazoleatypical antipsychotic · same class	Schizophrenia	1 labeler	$49.50 per tablet 0.25 mg tablet	Yes	No current entry
Cariprazineatypical antipsychotic · same class	Schizophrenia	none listed	$50.84 per capsule 1.5 mg capsule	Yes	No current entry
Lumateperoneatypical antipsychotic · same class	Schizophrenia	none listed	$57.24 per capsule 10.5 mg capsule	Yes	No current entry
Haloperidoltypical antipsychotic	Schizophrenia	28 labelers	$0.181 per tablet 5 mg tablet	Yes	A presentation being discontinued
Chlorpromazinephenothiazine	Schizophrenia	22 labelers	$0.552 per tablet 100 mg tablet	Yes	No current entry
Perphenazinephenothiazine	Schizophrenia	16 labelers	$0.161 per tablet 4 mg tablet	Yes	No current entry
Loxapine	Schizophrenia	7 labelers	$0.468 per capsule 10 mg capsule	Yes	No current entry
Trifluoperazinephenothiazine	Schizophrenia	6 labelers	$0.579 per tablet 2 mg tablet	Yes	No current entry
Milsaperidone	Schizophrenia	none listed	n/a	Yes	No current entry
Thiothixenetypical antipsychotic	Schizophrenia	4 labelers	$1.72 per capsule 10 mg capsule	Yes	No current entry
Molindonetypical antipsychotic	Schizophrenia	1 labeler	n/a	Yes	No current entry
Trospium and xanomelinecholinergic muscarinic agonist	Schizophrenia	none listed	$30.13 per capsule 100 mg-20 mg capsule	No	No current entry

Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)

What do pharmacies pay for each?

The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What next?

Clozapine: the full record: label, generics, price, shortages, recalls
Quetiapine vs clozapine: two records side by side
Clozapine vs olanzapine: two records side by side
Paliperidone vs clozapine: two records side by side
Clozapine vs haloperidol: two records side by side