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Medicines labeled for the same conditions

Alternatives to cilastatin and imipenem and relebactam

12 other medicines are given the same way (intravenous) and in the same FDA class as cilastatin and imipenem and relebactam or labeled mainly for the same use (urinary tract infections); 3 are in its class, renal dehydropeptidase inhibitors: avibactam and ceftazidime, ceftolozane and tazobactam and meropenem and vaborbactam; the others include 5 cephalosporin antibacterials and 2 tetracycline-class drugs (FDA labels read October 8, 2026).

Which medicines are labeled for the same conditions as cilastatin and imipenem and relebactam?

Urinary tract infections lists all 39 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.

Medicine and FDA classShared indicationGeneric labelers (intravenous)Pharmacy costBoxed warningShortage
Cilastatin and imipenem and relebactamrenal dehydropeptidase inhibitorthis medicinenone listedn/aNoA presentation being discontinued
Avibactam and ceftazidimebeta lactamase inhibitor · same classUrinary tract infectionsnone listedn/aNoNo current entry
Ceftolozane and tazobactambeta lactamase inhibitor · same classUrinary tract infectionsnone listedn/aNoNo current entry
Meropenem and vaborbactampenem antibacterial · same classUrinary tract infectionsnone listedn/aNoNo current entry
Doxycyclinetetracycline-class drugUrinary tract infections20 labelersn/aNoA presentation being discontinued
Cefazolincephalosporin antibacterialUrinary tract infections7 labelers$1.07 per vial 1 g vialNoNo current entry
Cefepimecephalosporin antibacterialUrinary tract infections8 labelersn/aNoA presentation being discontinued
Ceftriaxonecephalosporin antibacterialUrinary tract infections7 labelers$1.44 per vial 1 g vialNoNo current entry
PlazomicinUrinary tract infectionsnone listedn/aYesNo current entry
Cefepime and zidebactamcephalosporin antibacterialUrinary tract infectionsnone listedn/aNoNo current entry
Cefiderocolcephalosporin antibacterialUrinary tract infectionsnone listedn/aNoNo current entry
FosfomycinUrinary tract infectionsnone listedn/aNoNo current entry
Minocyclinetetracycline-class drugUrinary tract infectionsnone listedn/aNoNo current entry

Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)

What do pharmacies pay for each?

The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What next?

Cilastatin and imipenem and relebactam: the full record
label, generics, price, shortages, recalls