FDA Drug Shortage Database
Valproic acid (Depakene) shortage
No valproic acid presentation is listed as limited or unavailable in the FDA Drug Shortage Database (read October 8, 2026); it keeps 2 current entries listed as available (updated September 18, 2026). ASHP keeps a separate shortage list, which can differ.
- Generic listed
- Boxed warning
Check it at the source: the FDA Drug Shortage Database.
Which strengths are short?
| Strength | Limited or unavailable now | Listed now, available | Resolved or discontinued |
|---|---|---|---|
| 100mg/1ml injection | 0 | 1 | 0 |
| 500mg/5ml injection | 0 | 1 | 0 |
Which presentations are listed?
Listed now, available (2)
| Presentation | Company | Status and dates | Availability and reason given |
|---|---|---|---|
| Valproate Sodium, Injection, 100 mg/1 mL (NDC 63323-494-05) | Fresenius Kabi USA, LLC | Current posted December 30, 2020, updated September 15, 2026 | Available |
| Valproate Sodium, Injection, 500 mg/5 mL (NDC 0143-9785-10) | Hikma Pharmaceuticals USA, Inc. | Current posted December 30, 2020, updated September 18, 2026 | Available |
Source: FDA Drug Shortage Database via openFDA, read October 8, 2026
Are medicines for the same conditions short too?
Medicines whose labels share an indication with this one, and their own shortage status; listed as records, not substitutes.
| Medicine | Shared indication | Shortage | Generic labelers | Pharmacy cost |
|---|---|---|---|---|
| Gabapentin | Seizures and epilepsy | No current entry | 85 labelers | $0.0218 per capsule 100 mg capsule |
| Lamotrigine | Seizures and epilepsy | A presentation being discontinued | 49 labelers | $0.0268 per tablet 25 mg tablet |
| Divalproex | Seizures and epilepsy, Migraine | No current entry | 44 labelers | $0.194 per tablet 500 mg tablet |
| Carbamazepine | Seizures and epilepsy | A presentation being discontinued | 42 labelers | $0.119 per tablet 200 mg tablet |
| Oxcarbazepine | Seizures and epilepsy | No current entry | 43 labelers | $0.167 per tablet 300 mg tablet |
| Zonisamide | Seizures and epilepsy | No current entry | 20 labelers | $0.106 per capsule 100 mg capsule |
| Phenytoin | Seizures and epilepsy | No current entry | 29 labelers | $0.145 per capsule 100 mg capsule |
| Primidone | Seizures and epilepsy | No current entry | 21 labelers | $0.0914 per tablet 50 mg tablet |
| Felbamate | Seizures and epilepsy | No current entry | 9 labelers | $1.00 per tablet 600 mg tablet |
| Ethosuximide | Seizures and epilepsy | No current entry | 9 labelers | $0.243 per capsule 250 mg capsule |
| Tiagabine | Seizures and epilepsy | A presentation being discontinued | 2 labelers | $2.62 per tablet 2 mg tablet |
| Methsuximide | Seizures and epilepsy | No current entry | 1 labeler | $4.40 per capsule 300 mg capsule |
Source: FDA drug labels, FDA Drug Shortage Database, NDC Directory, CMS NADAC of October 7, 2026 (FDA files October 8, 2026)
What next?
- Every shortage now
- medicines by presentations in shortage