DEA controlled substances

Schedule II drugs

33 medicines are listed in FDA's NDC Directory with DEA schedule II; 29 are listed from generic labelers (directory read October 8, 2026).

Which medicines are schedule II?

The schedule is the one listed on the products; the DEA's own schedules decide the law.

Recalls: FDA enforcement reports, 2012 on
Medicine	Brand names	Generic labelers (all forms)	Pharmacy cost	Boxed warning	Shortage	Recalls since 2012
Methylphenidate	Metadate, Relexxii, Ritalin	31 labelers	$0.158 per tablet 10 mg tablet	Yes	In shortage	55
Amphetamine and dextroamphetamine	Adderall, Mydayis	25 labelers	$0.233 per tablet 10 mg tablet	Yes	In shortage	23
Acetaminophen and hydrocodone	Norco	36 labelers	$0.152 per tablet 10-325 mg tablet	Yes	No current entry	14
Lisdexamfetamine	Vyvanse, Arynta	19 labelers	$2.44 per capsule 20 mg capsule	Yes	In shortage	11
Oxycodone	Oxycontin, Xtampza, Roxybond	32 labelers	$0.0884 per tablet 5 mg tablet	Yes	No current entry	11
Morphine	Duramorph, Infumorph, Mitigo	22 labelers	$0.226 per tablet 15 mg tablet	Yes	In shortage	66
Acetaminophen and oxycodone	Endocet, Prolate, Percocet	29 labelers	$0.183 per tablet 7.5-325 mg tablet	Yes	A presentation being discontinued	8
Dexmethylphenidate	Focalin	13 labelers	$1.45 per capsule 10 mg capsule	Yes	No current entry	2
Acetaminophen and codeine	none listed	24 labelers	$0.256 per tablet 3 tablet	Yes	No current entry	5
Hydromorphone	Dilaudid	13 labelers	$0.219 per tablet 4 mg tablet	Yes	In shortage	30
Dextroamphetamine	Xelstrym, Dexedrine, Zenzedi	14 labelers	$0.373 per tablet 10 mg tablet	Yes	No current entry	24
Amphetamine	Adzenys, Dyanavel, Evekeo	13 labelers	$0.449 per tablet 10 mg tablet	Yes	No current entry	0
Fentanyl	none listed	6 labelers	$1.79 per mL 100 mcg/2 mL vial	Yes	In shortage	111
Methadone	Diskets	18 labelers	$0.177 per tablet 10 mg tablet	Yes	No current entry	4
Oxymorphone	none listed	9 labelers	n/a	Yes	No current entry	0
Tapentadol	Nucynta	4 labelers	$14.48 per tablet 100 mg tablet	Yes	No current entry	0
Hydrocodone	Hysingla	1 labeler	$7.95 per capsule 15 mg capsule	Yes	No current entry	0
Dronabinol	Marinol, Syndros	1 labeler	$3.35 per capsule 5 mg capsule	No	No current entry	0
Remifentanil	Ultiva	2 labelers	n/a	Yes	In shortage	0
Levorphanol	none listed	7 labelers	$10.65 per tablet 2 mg tablet	Yes	No current entry	0
Meperidine	Demerol	3 labelers	$0.157 per mL 50 mg/5 mL solution	Yes	Listed; available	0
Homatropine methylbromide and hydrocodone	none listed	3 labelers	$0.922 per tablet 5-1.5 mg tablet	Yes	No current entry	5
Codeine	none listed	1 labeler	$0.726 per tablet 30 mg tablet	Yes	No current entry	0
Hydrocodone and ibuprofen	none listed	2 labelers	$0.487 per unit 7.5-200	Yes	No current entry	0
Cocaine	Numbrino, Goprelto	none listed	n/a	Yes	No current entry	0
Acetaminophen and benzhydrocodone	Apadaz	none listed	n/a	Yes	No current entry	1
Chlorpheniramine and hydrocodone	none listed	2 labelers	$0.556 per mL Hydrocodone-chlorphen ER suspension	Yes	No current entry	1
Dexmethylphenidate and serdexmethylphenidate	Azstarys	none listed	$14.40 per capsule 26.1 mg-5.2 mg capsule	Yes	No current entry	0
Methamphetamine	none listed	3 labelers	$5.10 per tablet 5 mg tablet	Yes	No current entry	0
Oliceridine	Olinvyk	none listed	n/a	Yes	No current entry	0
Pentobarbital	none listed	2 labelers	n/a	No	No current entry	0
Aspirin and oxycodone	none listed	1 labeler	n/a	Yes	No current entry	0
Sufentanil	none listed	1 labeler	n/a	Yes	In shortage	1

Source: FDA NDC Directory (DEA schedule field) via openFDA, October 8, 2026; the DEA schedules