What the FDA labels say about taking them together
Risperidone and valproic acid
Neither FDA label names the other in its interaction, contraindication or warning sections. A label lists the interactions its studies and reports found; it is not a complete list, so ask a pharmacist before combining medicines. Labels read October 8, 2026.
Check it at the source: the risperidone FDA label on DailyMed (effective May 28, 2026, Janssen Pharmaceuticals, Inc.); the valproic acid FDA label on DailyMed (effective January 24, 2025, PAI Holdings, LLC dba PAI Pharma).
What does the risperidone label say about valproic acid?
Risperidone's label (effective May 28, 2026) and its 3 other brand-application labels do not name valproic acid in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (RISPERDAL), Janssen Pharmaceuticals, Inc., effective May 28, 2026 (SPL set 7e117c7e-02fc-4343-92a1-230061dfc5e0), via openFDA; the full label on DailyMed
What does the valproic acid label say about risperidone?
Valproic acid's label (effective January 24, 2025) does not name risperidone in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (VALPROIC ACID), PAI Holdings, LLC dba PAI Pharma, effective January 24, 2025 (SPL set 7d5cb52e-37dd-4dfa-a6f4-09f9548846c6), via openFDA; the full label on DailyMed
A pharmacist or prescriber can say whether these two medicines suit one person together; PlainMeds does not grade interactions.
Both medicines on the record
| Risperidone | Valproic acid | |
|---|---|---|
| Labeled for | Bipolar disorder, Schizophrenia | Seizures and epilepsy, Migraine |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $0.0368 per tablet 0.25 mg tablet | $0.243 per capsule 250 mg capsule |
| Shortage now | No current entry | Listed; available |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once