Metoprolol · more major-labeled pairs than Desvenlafaxine
SPL labels Metoprolol + Desvenlafaxine as minor; Metoprolol 14 / Desvenlafaxine 13 in that band.
Mechanism on file: Desvenlafaxine does not interfere with the way your body breaks down metoprolol.
FDA SPL severity: Minor
Metoprolol + Desvenlafaxine · SPL mechanism field
Desvenlafaxine does not interfere with the way your body breaks down metoprolol.
Minor band excerpt · Metoprolol with Desvenlafaxine
Examples desipramine, atomoxetine, dextromethorphan, metoprolol, nebivolol, perphenazine, tolterodine 7.2 Drugs Having No Clinically Important Interactions with PRISTIQ Based on pharmacokinetic studies, no dosage adjustment is required for drugs that are mainly metabolized by CYP3A4 (e.g., midazolam), or for drugs that are metabolized by both CYP2D6 and CYP3A4 (e.g., tamoxifen, aripiprazole), when administered concomitantly with PRISTIQ [see Clinical Pharmacology (12.3) ].
Metoprolol · 1 major-labeled pairs (vs Desvenlafaxine's 0)
- Bupropion minor
- Darunavir minor
- Dronedarone minor
- Epinephrine minor
Desvenlafaxine · 19 SPL pairs (broader portfolio than Metoprolol)
- Aripiprazole minor
- Atomoxetine minor
- Buspirone minor
- Desipramine minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.