Dronedarone · more major-labeled pairs than Metoprolol
SPL labels Metoprolol + Dronedarone as minor; Metoprolol 14 / Dronedarone 8 in that band.
Mechanism on file: Dronedarone makes it harder for the body to process metoprolol. This causes the amount of metoprolol in your blood to go up.
FDA SPL severity: Minor
Metoprolol + Dronedarone · SPL mechanism field
Dronedarone makes it harder for the body to process metoprolol. This causes the amount of metoprolol in your blood to go up.
Minor band excerpt · Metoprolol with Dronedarone
Beta-Blockers and Other CYP2D6 Substrates Dronedarone increased the exposure of propranolol and metoprolol.
Metoprolol · 14 minor + 18 total pairs
- Bupropion minor
- Darunavir minor
- Desvenlafaxine minor
- Epinephrine minor
Dronedarone · 9 major-labeled pairs (vs Metoprolol's 1)
- Dabigatran minor
- Digoxin minor
- Diltiazem minor
- Nifedipine minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.