Desvenlafaxine · larger labeled portfolio than Desipramine
SPL labels Desvenlafaxine + Desipramine as minor; Desvenlafaxine 13 / Desipramine 18 in that band.
Mechanism on file: Desvenlafaxine may interfere with the way your body breaks down desipramine, potentially leading to higher levels of the medication in your blood.
FDA SPL severity: Minor
Desvenlafaxine + Desipramine · SPL mechanism field
Desvenlafaxine may interfere with the way your body breaks down desipramine, potentially leading to higher levels of the medication in your blood.
Minor band excerpt · Desvenlafaxine with Desipramine
Examples desipramine, atomoxetine, dextromethorphan, metoprolol, nebivolol, perphenazine, tolterodine 7.2 Drugs Having No Clinically Important Interactions with PRISTIQ Based on pharmacokinetic studies, no dosage adjustment is required for drugs that are mainly metabolized by CYP3A4 (e.g., midazolam), or for drugs that are metabolized by both CYP2D6 and CYP3A4 (e.g., tamoxifen, aripiprazole), when administered concomitantly with PRISTIQ [see Clinical Pharmacology (12.3) ].
Desvenlafaxine · 19 SPL pairs (broader portfolio than Desipramine)
- Aripiprazole minor
- Atomoxetine minor
- Buspirone minor
- Dextromethorphan minor
Desipramine · 18 minor + 18 total pairs
- Atomoxetine minor
- Bupropion minor
- Darunavir minor
- Dopamine minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.